Toxicology

Amy J. Clippinger, Hans A. Raabe, David G. Allen, et al. Human-relevant approaches to assess eye corrosion/irritation potential of agrochemical formulations. Cutaneous and Ocular Toxicology. 2021;40(2):145-167. doi:10.1080/15569527.2021.1910291

Bérénice Charrez, Verena Charwat, Brian Siemons, et al. In vitro safety “clinical trial” of the cardiac liability of drug polytherapy. Clinical and Translational Science. 2021;14(3):1155-1165. doi:10.1111/cts.13038

David B. Chou, Viktoras Frismantas, Yuka Milton, et al. On-chip recapitulation of clinical bone marrow toxicities and patient-specific pathophysiology. Nature Biomedical Engineering. 2020;4(4):394-406. doi:10.1038/s41551-019-0495-z

Mark Schurdak, Lawrence Vernetti, Luke Bergenthal, et al. Applications of the microphysiology systems database for experimental ADME-Tox and disease models. Lab on a Chip. 2020;20(8):1472-1492. doi:10.1039/C9LC01047E

Gopal Pawar, Judith C. Madden, David Ebbrell, James W. Firman, Mark T. D. Cronin. In Silico Toxicology Data Resources to Support Read-Across and (Q)SAR. Frontiers in Pharmacology. 2019;10. https://www.frontiersin.org/articles/10.3389/fphar.2019.00561.

Michael Balls, Jarrod Bailey, Robert D. Combes. How viable are alternatives to animal testing in determining the toxicities of therapeutic drugs?. Expert Opinion on Drug Metabolism & Toxicology. 2019;15(12):985-987. doi:10.1080/17425255.2019.1694662

Kyung-Jin Jang, Monicah A. Otieno, Janey Ronxhi, et al. Reproducing human and cross-species drug toxicities using a Liver-Chip. Science Translational Medicine. 2019;11(517):eaax5516. doi:10.1126/scitranslmed.aax5516

Catherine Mahony. Building confidence in non-animal methods: Practical examples of collaboration between regulators, researchers and industry. Computational Toxicology. 2019;10:78-80. doi:10.1016/j.comtox.2019.01.003

Nicole C. Kleinstreuer, Sebastian Hoffmann, Nathalie Alépée, et al. Non-animal methods to predict skin sensitization (II): an assessment of defined approaches. Critical Reviews in Toxicology. 2018;48(5):359-374. doi:10.1080/10408444.2018.1429386

Rebecca L. Morgan, Paul Whaley, Kristina A. Thayer, Holger J. Schünemann. Identifying the PECO: A framework for formulating good questions to explore the association of environmental and other exposures with health outcomes. Environment International. 2018;121:1027-1031. doi:10.1016/j.envint.2018.07.015