Can Animal Models of Disease Reliably Inform Human Studies?

H. Bart van der Worp, David W. Howells, Emily S. Sena, Michelle J. Porritt, Sarah Rewell, Victoria O'Collins, Malcolm R. Macleod
PLOS Medicine. ;7(3):e1000245. doi: 10.1371/journal.pmed.1000245

H. Bart van der Worp and colleagues discuss the controversies and possibilities of translating the results of animal experiments into human clinical trials.

https://journals.plos.org/plosmedicine/article?id=10.1371/journal.pmed.1000245
Keywords
animal models
Animal models of disease
animal studies
clinical trials
Ischemic Stroke
Metaanalysis
Publication ethics
Systematic reviews
Library Collection(s)
Translation and validation
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