Preclinical research

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Thomas Hartung. The (misleading) role of animal models in drug development. Frontiers in Drug Discovery. 2024;4. doi:10.3389/fddsv.2024.1355044
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Sonya Kouthouridis, Eleanor Robson, Alicia Hartung, Sandeep Raha, Boyang Zhang. Se(XY) matters: the importance of incorporating sex in microphysiological models. Trends in Biotechnology. 2022;40(11):1284-1298. doi:10.1016/j.tibtech.2022.04.005
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Jack W. Scannell, James Bosley, John A. Hickman, et al. Predictive validity in drug discovery: what it is, why it matters and how to improve it. Nature Reviews Drug Discovery. 2022;21(12):915-931. doi:10.1038/s41573-022-00552-x
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Larry Carbone. Estimating mouse and rat use in American laboratories by extrapolation from Animal Welfare Act-regulated species. Scientific Reports. 2021;11(1):493. doi:10.1038/s41598-020-79961-0
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Partho Protim Adhikary, Qurrat Ul Ain, Andreas Christian Hocke, Sarah Hedtrich. COVID-19 highlights the model dilemma in biomedical research. Nature Reviews Materials. 2021;6(5):374-376. doi:10.1038/s41578-021-00305-z
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