Humans

Hongbing Wang, Paul C. Brown, Edwin C. Y. Chow, et al. 3D cell culture models: Drug pharmacokinetics, safety assessment, and regulatory consideration. Clinical and Translational Science. 2021;14(5):1659-1680. doi:10.1111/cts.13066

Lorna Ewart, Adrian Roth. Opportunities and challenges with microphysiological systems: a pharma end-user perspective. Nature Reviews. Drug Discovery. 2021;20(5):327-328. doi:10.1038/d41573-020-00030-2

Amanda M. Clark, Nancy L. Allbritton, Alan Wells. Integrative microphysiological tissue systems of cancer metastasis to the liver. Seminars in Cancer Biology. 2021;71:157-169. doi:10.1016/j.semcancer.2020.06.010

Jarrod Bailey. Biomedical Research Must Change - But a Shift Toward Human-specific Research Methods Is Only Part of What Is Needed. Alternatives to Laboratory Animals. 2021;49(3):69-72. doi:10.1177/02611929211030417

Jennifer M. McCracken, Gisele A. Calderon, Andrew J. Robinson, Courtney N. Sullivan, Elizabeth Cosgriff-Hernandez, Julie C. E. Hakim. Animal Models and Alternatives in Vaginal Research: a Comparative Review. Reproductive Sciences. 2021;28(6):1759-1773. doi:10.1007/s43032-021-00529-y

Mario Gaudino, N. Bryce Robinson, Antonino Di Franco, et al. Effects of Experimental Interventions to Improve the Biomedical Peer-Review Process: A Systematic Review and Meta-Analysis. Journal of the American Heart Association. 2021;10(15):e019903. doi:10.1161/JAHA.120.019903

Julie Jerber, Daniel D. Seaton, Anna S. E. Cuomo, et al. Population-scale single-cell RNA-seq profiling across dopaminergic neuron differentiation. Nature Genetics. 2021;53(3):304-312. doi:10.1038/s41588-021-00801-6

Tengku Ibrahim Maulana, Elena Kromidas, Lars Wallstabe, et al. Immunocompetent cancer-on-chip models to assess immuno-oncology therapy. Advanced Drug Delivery Reviews. 2021;173:281-305. doi:10.1016/j.addr.2021.03.015

Julia M. L. Menon, Merel Ritskes-Hoitinga, Pandora Pound, Erica van Oort. The impact of conducting preclinical systematic reviews on researchers and their research: A mixed method case study. PloS One. 2021;16(12):e0260619. doi:10.1371/journal.pone.0260619

Gabriela S. Kronemberger, Fabiana A. Carneiro, Danielle F. Rezende, Leandra S. Baptista. Spheroids and organoids as humanized 3D scaffold-free engineered tissues for SARS-CoV-2 viral infection and drug screening. Artificial Organs. 2021;45(6):548-558. doi:10.1111/aor.13880