Humans

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Eric Vallabh Minikel, Konrad J. Karczewski, Hilary C. Martin, et al. Evaluating drug targets through human loss-of-function genetic variation. Nature. 2020;581(7809):459-464. doi:10.1038/s41586-020-2267-z
View Full Reference
1.
Mart M. Lamers, Joep Beumer, Jelte van der Vaart, et al. SARS-CoV-2 productively infects human gut enterocytes. Science (New York, N.Y.). 2020;369(6499):50-54. doi:10.1126/science.abc1669
View Full Reference
1.
Kanako Yuki, Ning Cheng, Michitaka Nakano, Calvin J. Kuo. Organoid Models of Tumor Immunology. Trends in Immunology. 2020;41(8):652-664. doi:10.1016/j.it.2020.06.010
View Full Reference
1.
Jie Zhou, Cun Li, Xiaojuan Liu, et al. Infection of bat and human intestinal organoids by SARS-CoV-2. Nature Medicine. 2020;26(7):1077-1083. doi:10.1038/s41591-020-0912-6
View Full Reference
1.
S. Vincent Rajkumar. The high cost of prescription drugs: causes and solutions. Blood Cancer Journal. 2020;10(6):71. doi:10.1038/s41408-020-0338-x
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Patrick M. Misun, Burçak Yesildag, Felix Forschler, et al. In Vitro Platform for Studying Human Insulin Release Dynamics of Single Pancreatic Islet Microtissues at High Resolution. Advanced Biosystems. 2020;4(3):e1900291. doi:10.1002/adbi.201900291
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Uwe Marx, Takafumi Akabane, Tommy B. Andersson, et al. Biology-inspired microphysiological systems to advance patient benefit and animal welfare in drug development. ALTEX. 2020;37(3):365-394. doi:10.14573/altex.2001241
View Full Reference
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Sunghee Estelle Park, Andrei Georgescu, Dongeun Huh. Organoids-on-a-chip. Science (New York, N.Y.). 2019;364(6444):960-965. doi:10.1126/science.aaw7894
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Elizabeth J. Baker, Nancy A. Beck, Ellen L. Berg, et al. Advancing nonclinical innovation and safety in pharmaceutical testing. Drug Discovery Today. 2019;24(2):624-628. doi:10.1016/j.drudis.2018.11.011
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David Tuveson, Hans Clevers. Cancer modeling meets human organoid technology. Science (New York, N.Y.). 2019;364(6444):952-955. doi:10.1126/science.aaw6985
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