Humans

Vivek V. Thacker, Kunal Sharma, Neeraj Dhar, Gian-Filippo Mancini, Jessica Sordet-Dessimoz, John D. McKinney. Rapid endotheliitis and vascular damage characterize SARS-CoV-2 infection in a human lung-on-chip model. EMBO reports. 2021;22(6):e52744. doi:10.15252/embr.202152744

Lucie A. Low, Christine Mummery, Brian R. Berridge, Christopher P. Austin, Danilo A. Tagle. Organs-on-chips: into the next decade. Nature Reviews. Drug Discovery. 2021;20(5):345-361. doi:10.1038/s41573-020-0079-3

Yuling Han, Xiaohua Duan, Liuliu Yang, et al. Identification of SARS-CoV-2 inhibitors using lung and colonic organoids. Nature. 2021;589(7841):270-275. doi:10.1038/s41586-020-2901-9

Foluwasomi A. Oyefeso, Alysson R. Muotri, Christopher G. Wilson, Michael J. Pecaut. Brain organoids: A promising model to assess oxidative stress-induced central nervous system damage. Developmental Neurobiology. 2021;81(5):653-670. doi:10.1002/dneu.22828

Abbas Shafiee, Lida Moradi, Mayasari Lim, Jason Brown. Coronavirus disease 2019: A tissue engineering and regenerative medicine perspective. Stem Cells Translational Medicine. 2021;10(1):27-38. doi:10.1002/sctm.20-0197

Monica Piergiovanni, Ozlem Cangar, Sofia B. Leite, et al. Putting Science into Standards workshop on standards for organ-on-chip. Stem Cell Reports. 2021;16(9):2076-2077. doi:10.1016/j.stemcr.2021.07.010

Valentina Paloschi, Maria Sabater-Lleal, Heleen Middelkamp, et al. Organ-on-a-chip technology: a novel approach to investigate cardiovascular diseases. Cardiovascular Research. 2021;117(14):2742-2754. doi:10.1093/cvr/cvab088

Louisa Helms, Silvia Marchiano, Ian B. Stanaway, et al. Cross-validation of SARS-CoV-2 responses in kidney organoids and clinical populations. JCI insight. 2021;6(24):e154882. doi:10.1172/jci.insight.154882

Sabrina Ehnert, Helen Rinderknecht, Romina H. Aspera-Werz, Victor Häussling, Andreas K. Nussler. Use of in vitro bone models to screen for altered bone metabolism, osteopathies, and fracture healing: challenges of complex models. Archives of Toxicology. 2020;94(12):3937-3958. doi:10.1007/s00204-020-02906-z

Yotam E. Bar-Ephraim, Kai Kretzschmar, Hans Clevers. Organoids in immunological research. Nature Reviews. Immunology. 2020;20(5):279-293. doi:10.1038/s41577-019-0248-y