Humans

Christoph Bock, Michael Boutros, J. Gray Camp, et al. The Organoid Cell Atlas. Nature Biotechnology. 2021;39(1):13-17. doi:10.1038/s41587-020-00762-x

Lorna Ewart, Adrian Roth. Opportunities and challenges with microphysiological systems: a pharma end-user perspective. Nature Reviews. Drug Discovery. 2021;20(5):327-328. doi:10.1038/d41573-020-00030-2

Jens Puschhof, Cayetano Pleguezuelos-Manzano, Hans Clevers. Organoids and organs-on-chips: Insights into human gut-microbe interactions. Cell Host & Microbe. 2021;29(6):867-878. doi:10.1016/j.chom.2021.04.002

Bruna A. G. de Melo, Julia C. Benincasa, Elisa M. Cruz, Juliana Terzi Maricato, Marimelia A. Porcionatto. 3D culture models to study SARS-CoV-2 infectivity and antiviral candidates: From spheroids to bioprinting. Biomedical Journal. 2021;44(1):31-42. doi:10.1016/j.bj.2020.11.009

Rasa Elmentaite, Natsuhiko Kumasaka, Kenny Roberts, et al. Cells of the human intestinal tract mapped across space and time. Nature. 2021;597(7875):250-255. doi:10.1038/s41586-021-03852-1

Michela Anna Polidoro, Erika Ferrari, Simona Marzorati, Ana Lleo, Marco Rasponi. Experimental liver models: From cell culture techniques to microfluidic organs-on-chip. Liver International: Official Journal of the International Association for the Study of the Liver. 2021;41(8):1744-1761. doi:10.1111/liv.14942

Julia M. L. Menon, Merel Ritskes-Hoitinga, Pandora Pound, Erica van Oort. The impact of conducting preclinical systematic reviews on researchers and their research: A mixed method case study. PloS One. 2021;16(12):e0260619. doi:10.1371/journal.pone.0260619

Gabriela S. Kronemberger, Fabiana A. Carneiro, Danielle F. Rezende, Leandra S. Baptista. Spheroids and organoids as humanized 3D scaffold-free engineered tissues for SARS-CoV-2 viral infection and drug screening. Artificial Organs. 2021;45(6):548-558. doi:10.1111/aor.13880

Vivek V. Thacker, Kunal Sharma, Neeraj Dhar, Gian-Filippo Mancini, Jessica Sordet-Dessimoz, John D. McKinney. Rapid endotheliitis and vascular damage characterize SARS-CoV-2 infection in a human lung-on-chip model. EMBO reports. 2021;22(6):e52744. doi:10.15252/embr.202152744

Lucie A. Low, Christine Mummery, Brian R. Berridge, Christopher P. Austin, Danilo A. Tagle. Organs-on-chips: into the next decade. Nature Reviews. Drug Discovery. 2021;20(5):345-361. doi:10.1038/s41573-020-0079-3