Humans

Amanda M. Clark, Nancy L. Allbritton, Alan Wells. Integrative microphysiological tissue systems of cancer metastasis to the liver. Seminars in Cancer Biology. 2021;71:157-169. doi:10.1016/j.semcancer.2020.06.010

Vivek V. Thacker, Kunal Sharma, Neeraj Dhar, Gian-Filippo Mancini, Jessica Sordet-Dessimoz, John D. McKinney. Rapid endotheliitis and vascular damage characterize SARS-CoV-2 infection in a human lung-on-chip model. EMBO reports. 2021;22(6):e52744. doi:10.15252/embr.202152744

Yuling Han, Xiaohua Duan, Liuliu Yang, et al. Identification of SARS-CoV-2 inhibitors using lung and colonic organoids. Nature. 2021;589(7841):270-275. doi:10.1038/s41586-020-2901-9

Jarrod Bailey. Biomedical Research Must Change - But a Shift Toward Human-specific Research Methods Is Only Part of What Is Needed. Alternatives to Laboratory Animals. 2021;49(3):69-72. doi:10.1177/02611929211030417

Monica Piergiovanni, Ozlem Cangar, Sofia B. Leite, et al. Putting Science into Standards workshop on standards for organ-on-chip. Stem Cell Reports. 2021;16(9):2076-2077. doi:10.1016/j.stemcr.2021.07.010

Louisa Helms, Silvia Marchiano, Ian B. Stanaway, et al. Cross-validation of SARS-CoV-2 responses in kidney organoids and clinical populations. JCI insight. 2021;6(24):e154882. doi:10.1172/jci.insight.154882

Jonas C. Schupp, Taylor S. Adams, Carlos Cosme, et al. Integrated Single-Cell Atlas of Endothelial Cells of the Human Lung. Circulation. 2021;144(4):286-302. doi:10.1161/CIRCULATIONAHA.120.052318

Michael S. Lauer, Jamie Doyle, Joy Wang, Deepshikha Roychowdhury. Associations of topic-specific peer review outcomes and institute and center award rates with funding disparities at the National Institutes of Health. eLife. 2021;10:e67173. doi:10.7554/eLife.67173

Lorna Ewart, Adrian Roth. Opportunities and challenges with microphysiological systems: a pharma end-user perspective. Nature Reviews. Drug Discovery. 2021;20(5):327-328. doi:10.1038/d41573-020-00030-2

Tomasz Kostrzewski, Sophie Snow, Anya Lindström Battle, et al. Modelling human liver fibrosis in the context of non-alcoholic steatohepatitis using a microphysiological system. Communications Biology. 2021;4(1):1080. doi:10.1038/s42003-021-02616-x