Humans

Sebastian Hoffmann, Paul Whaley, Katya Tsaioun. How evidence-based methodologies can help identify and reduce uncertainty in chemical risk assessment. ALTEX. 2022;39(2):175-182. doi:10.14573/altex.2201131

Tingting Tao, Pengwei Deng, Yaqing Wang, et al. Microengineered Multi-Organoid System from hiPSCs to Recapitulate Human Liver-Islet Axis in Normal and Type 2 Diabetes. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). 2022;9(5):e2103495. doi:10.1002/advs.202103495

Shengli Ding, Carolyn Hsu, Zhaohui Wang, et al. Patient-derived micro-organospheres enable clinical precision oncology. Cell Stem Cell. 2022;29(6):905-917.e6. doi:10.1016/j.stem.2022.04.006

Ivan Rusyn, Courtney Sakolish, Yuki Kato, et al. Microphysiological Systems Evaluation: Experience of TEX-VAL Tissue Chip Testing Consortium. Toxicological Sciences: An Official Journal of the Society of Toxicology. 2022;188(2):143-152. doi:10.1093/toxsci/kfac061

Zhong Alan Li, Rocky S. Tuan. Towards establishing human body-on-a-chip systems. Stem Cell Research & Therapy. 2022;13(1):431. doi:10.1186/s13287-022-03130-5

Drew E. Glaser, Matthew B. Curtis, Peter A. Sariano, et al. Organ-on-a-chip model of vascularized human bone marrow niches. Biomaterials. 2022;280:121245. doi:10.1016/j.biomaterials.2021.121245

Oliver L. Eichmüller, Juergen A. Knoblich. Human cerebral organoids - a new tool for clinical neurology research. Nature Reviews. Neurology. 2022;18(11):661-680. doi:10.1038/s41582-022-00723-9

Julio Sempere, Suélen Andreia Rossi, Irene Chamorro-Herrero, et al. Minilungs from Human Embryonic Stem Cells to Study the Interaction of Streptococcus pneumoniae with the Respiratory Tract. Microbiology Spectrum. 2022;10(3):e0045322. doi:10.1128/spectrum.00453-22

Anna J. van der Zalm, João Barroso, Patience Browne, et al. A framework for establishing scientific confidence in new approach methodologies. Archives of Toxicology. 2022;96:2865-2879. doi:10.1007/s00204-022-03365-4

Merel Ritskes-Hoitinga, Pandora Pound. The role of systematic reviews in identifying the limitations of preclinical animal research, 2000-2022: part 2. Journal of the Royal Society of Medicine. 2022;115(6):231-235. doi:10.1177/01410768221100970