Drug development

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S. Vincent Rajkumar. The high cost of prescription drugs: causes and solutions. Blood Cancer Journal. 2020;10(6):71. doi:10.1038/s41408-020-0338-x
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Gail A. Van Norman. Limitations of Animal Studies for Predicting Toxicity in Clinical Trials: Is it Time to Rethink Our Current Approach?. JACC. Basic to translational science. 2019;4(7):845-854. doi:10.1016/j.jacbts.2019.10.008
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Aroon D. Hingorani, Valerie Kuan, Chris Finan, et al. Improving the odds of drug development success through human genomics: modelling study. Scientific Reports. 2019;9(1):18911. doi:10.1038/s41598-019-54849-w
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Désirée H. Veening-Griffioen, Guilherme S. Ferreira, Peter J. K. Van Meer, et al. Are some animal models more equal than others? A case study on the translational value of animal models of efficacy for Alzheimer’s disease. European Journal of Pharmacology. 2019;859:172524. doi:10.1016/j.ejphar.2019.172524
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Michael Balls, Jarrod Bailey, Robert D. Combes. How viable are alternatives to animal testing in determining the toxicities of therapeutic drugs?. Expert Opinion on Drug Metabolism & Toxicology. 2019;15(12):985-987. doi:10.1080/17425255.2019.1694662
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A. Jain, R. Barrile, A. D. van der Meer, et al. Primary Human Lung Alveolus-on-a-chip Model of Intravascular Thrombosis for Assessment of Therapeutics. Clinical Pharmacology and Therapeutics. 2018;103(2):332-340. doi:10.1002/cpt.742
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Riccardo Barrile, Andries D. van der Meer, Hyoungshin Park, et al. Organ-on-Chip Recapitulates Thrombosis Induced by an anti-CD154 Monoclonal Antibody: Translational Potential of Advanced Microengineered Systems. Clinical Pharmacology and Therapeutics. 2018;104(6):1240-1248. doi:10.1002/cpt.1054
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Kacey Ronaldson-Bouchard, Gordana Vunjak-Novakovic. Organs-on-a-Chip: A Fast Track for Engineered Human Tissues in Drug Development. Cell Stem Cell. 2018;22(3):310-324. doi:10.1016/j.stem.2018.02.011
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Kacey Ronaldson-Bouchard, Gordana Vunjak-Novakovic. Organs-on-a-Chip: A Fast Track for Engineered Human Tissues in Drug Development. Cell Stem Cell. 2018;22(3):310-324. doi:10.1016/j.stem.2018.02.011
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