Translation and validation

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Susan Bridgwood Green. Can animal data translate to innovations necessary for a new era of patient-centred and individualised healthcare? Bias in preclinical animal research. BMC Medical Ethics. 2015;16:53. doi:10.1186/s12910-015-0043-7
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Aysha Akhtar. The Flaws and Human Harms of Animal Experimentation. Cambridge Quarterly of Healthcare Ethics. 2015;24(4):407-419. doi:10.1017/S0963180115000079
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Terry C. Burns, Matthew D. Li, Swapnil Mehta, Ahmed J. Awad, Alexander A. Morgan. Mouse models rarely mimic the transcriptome of human neurodegenerative diseases: A systematic bioinformatics-based critique of preclinical models. European Journal of Pharmacology. 2015;759:101-117. doi:10.1016/j.ejphar.2015.03.021
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Jarrod Bailey, Michelle Thew, Michael Balls. An analysis of the use of animal models in predicting human toxicology and drug safety. Alternatives to Laboratory Animals. 2014;42(3):181-199. doi:10.1177/026119291404200306
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Fiona Godlee. How predictive and productive is animal research?. BMJ. 2014;348:g3719. doi:10.1136/bmj.g3719
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Jarrod Bailey. Monkey-based research on human disease: the implications of genetic differences. Alternatives to Laboratory Animals. 2014;42(5):287-317. doi:10.1177/026119291404200504
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Isabella WY Mak, Nathan Evaniew, Michelle Ghert. Lost in translation: animal models and clinical trials in cancer treatment. American Journal of Translational Research. 2014;6(2):114-118. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3902221/.
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Jennifer A. Hirst, Jeremy Howick, Jeffrey K. Aronson, et al. The need for randomization in animal trials: an overview of systematic reviews. PloS One. 2014;9(6):e98856. doi:10.1371/journal.pone.0098856
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