Human cerebellar organoids with functional Purkinje cells

Alexander Atamian, Marcella Birtele, Negar Hosseini, Tuan Nguyen, Anoothi Seth, Ashley Del Dosso, Sandeep Paul, Neil Tedeschi, Ryan Taylor, Marcelo P. Coba, Ranmal Samarasinghe, Carlos Lois, Giorgia Quadrato

Cell Stem Cell. 2024;31(1):39-51.e6. doi: 10.1016/j.stem.2023.11.013

https://www.cell.com/cell-stem-cell/abstract/S1934-5909(23)00430-7

Keywords

functional Purkinje cells

human cerebellum

human pluripotent stem cell-derived organoids

human-specific rhombic lip subventricular zone

network activity

single-cell RNA sequencing

spatial transcriptomics

Library Collection(s)