1.
Vukasin M. Jovanovic, Narisu Narisu, Lori L. Bonnycastle, et al. Scalable hypothalamic neuron differentiation from human pluripotent stem cells suitable for modeling metabolic disorders. Stem Cell Reports. 2026. doi:10.1016/j.stemcr.2026.102958
Nervous system
1.
Sathish Selvam, Roberta S. Dos Reis, Marc C. E. Wagner, et al. Vascularized human brain organoids as a model of the brain–peripheral axis in HIV-1 neuropathogenesis. Scientific Reports. 2026. doi:10.1038/s41598-025-33940-5
1.
Matthew Price, Francesca Pistollato. Beyond the amyloid hypothesis: leveraging human-centered complex in vitro models to decode Alzheimer’s disease etiology. Frontiers in Toxicology. 2026;7. doi:10.3389/ftox.2025.1753572
1.
Ami Mehta-Doshi, Blake L. Tsu, Consuelo Sauceda, et al. Age-dependent neuroinflammatory effects of red blood cells and their exosomes in a human brain-on-chip model. Blood Red Cells & Iron. 2026;2(1):100044. doi:10.1016/j.brci.2025.100044
1.
Andrew N. Shen, Katelin S. Matazel, W. Drew Gill, Lorna Ewart, Randy S. Daughters, Hector Rosas-Hernandez. Modeling neurovascular dysfunction in Alzheimer’s disease using an isogenic brain-chip model. Fluids and Barriers of the CNS. 2026;23(1):1. doi:10.1186/s12987-025-00708-y
1.
Nozomu Takata, Zhiwei Li, Anna Metlushko, et al. Injury and therapy in a human spinal cord organoid. Nature Biomedical Engineering. 2026:1-14. doi:10.1038/s41551-025-01606-2
1.
Jade Admiraal, Promise O. Emeh, Marleen Bokkers, et al. Building the blood-brain barrier: a scalable self-assembling 3D model of the brain microvasculature under unidirectional flow. Fluids and Barriers of the CNS. 2026;23(1):29. doi:10.1186/s12987-026-00765-x
1.
Nisim Perets, Liya Kerem, Nir Waiskopf, et al. Patient-derived brain organoids reveal divergent neuronal activity across subpopulations of autism spectrum disorder. Translational Psychiatry. 2026. doi:10.1038/s41398-026-03890-1
1.
Ahmed Disouky, Mark A. Sanborn, K. R. Sabitha, et al. Human hippocampal neurogenesis in adulthood, ageing and Alzheimer’s disease. Nature. 2026:1-10. doi:10.1038/s41586-026-10169-4
1.
Tatsuya Osaki, Chloe Delepine, Yuma Osako, et al. Early differential impact of MeCP2 mutations on functional networks in Rett syndrome patient-derived human cortical organoids. Nature Communications. 2026. doi:10.1038/s41467-026-71458-0