Nervous system

Dana M. Cairns, Brooke M. Smiley, Jordan A. Smiley, et al. Repetitive injury induces phenotypes associated with Alzheimer’s disease by reactivating HSV-1 in a human brain tissue model. Science Signaling. 2025;18(868):eado6430. doi:10.1126/scisignal.ado6430

Jakub Scaber, Iona Thomas-Wright, Alex J. Clark, et al. Cellular and axonal transport phenotypes due to the C9ORF72 HRE in iPSC motor and sensory neurons. Stem Cell Reports. 2024;19(7):957-972. doi:10.1016/j.stemcr.2024.05.008

Neal D. Amin, Kevin W. Kelley, Konstantin Kaganovsky, et al. Generating human neural diversity with a multiplexed morphogen screen in organoids. Cell Stem Cell. 2024;31(12):1831-1846.e9. doi:10.1016/j.stem.2024.10.016

Dennis M. Nahon, Marc Vila Cuenca, Francijna E. van den Hil, et al. Self-assembling 3D vessel-on-chip model with hiPSC-derived astrocytes. Stem Cell Reports. 2024;19(7):946-956. doi:10.1016/j.stemcr.2024.05.006

Dorit Trudler, Swagata Ghatak, Michael Bula, et al. Dysregulation of miRNA expression and excitation in MEF2C autism patient hiPSC-neurons and cerebral organoids. Molecular Psychiatry. 2024:1-18. doi:10.1038/s41380-024-02761-9

Diana Tavares Ferreira, Breanna Q. Shen, Juliet M. Mwirigi, et al. Deciphering the Molecular Landscape of Human Peripheral Nerves: Implications for Diabetic Peripheral Neuropathy.; 2024. doi:10.1101/2024.06.15.599167

Tyler J. Wenzel, Darrell D. Mousseau. Brain organoids engineered to give rise to glia and neural networks after 90 days in culture exhibit human-specific proteoforms. Frontiers in Cellular Neuroscience. 2024;18. doi:10.3389/fncel.2024.1383688

Alexander Atamian, Marcella Birtele, Negar Hosseini, et al. Human cerebellar organoids with functional Purkinje cells. Cell Stem Cell. 2024;31(1):39-51.e6. doi:10.1016/j.stem.2023.11.013

Lena Smirnova, Thomas Hartung. The Promise and Potential of Brain Organoids. Advanced Healthcare Materials. 2024;13(21):2302745. doi:10.1002/adhm.202302745

Adrià Casamitjana, Matteo Mancini, Eleanor Robinson, et al. A Next-Generation, Histological Atlas of the Human Brain and Its Application to Automated Brain MRI Segmentation.; 2024. doi:10.1101/2024.02.05.579016