Humans

Janet Piñero, Laura I. Furlong, Ferran Sanz. In silico models in drug development: where we are. Current Opinion in Pharmacology. 2018;42:111-121. doi:10.1016/j.coph.2018.08.007

Sang Hun Lee, SoonGweon Hong, Jihwan Song, et al. Microphysiological Analysis Platform of Pancreatic Islet β-Cell Spheroids. Advanced Healthcare Materials. 2018;7(2). doi:10.1002/adhm.201701111

Dorothée Diogo, Chao Tian, Christopher S. Franklin, et al. Phenome-wide association studies across large population cohorts support drug target validation. Nature Communications. 2018;9(1):4285. doi:10.1038/s41467-018-06540-3

A. S. Khazali, A. M. Clark, A. Wells. A Pathway to Personalizing Therapy for Metastases Using Liver-on-a-Chip Platforms. Stem Cell Reviews and Reports. 2017;13(3):364-380. doi:10.1007/s12015-017-9735-3

Eduard Batlle, Hans Clevers. Cancer stem cells revisited. Nature Medicine. 2017;23(10):1124-1134. doi:10.1038/nm.4409

William G. Kaelin. Common pitfalls in preclinical cancer target validation. Nature Reviews. Cancer. 2017;17(7):425-440. doi:10.1038/nrc.2017.32

Shuo Xiao, Jonathan R. Coppeta, Hunter B. Rogers, et al. A microfluidic culture model of the human reproductive tract and 28-day menstrual cycle. Nature Communications. 2017;8:14584. doi:10.1038/ncomms14584

Melody Mills, Mary K. Estes. Physiologically relevant human tissue models for infectious diseases. Drug Discovery Today. 2016;21(9):1540-1552. doi:10.1016/j.drudis.2016.06.020

Vijay Pal Singh, Kunal Pratap, Juhi Sinha, Koundinya Desiraju, Devika Bahal, Ritushree Kukreti. Critical evaluation of challenges and future use of animals in experimentation for biomedical research. International Journal of Immunopathology and Pharmacology. 2016;29(4):551-561. doi:10.1177/0394632016671728

Hans Clevers. Modeling Development and Disease with Organoids. Cell. 2016;165(7):1586-1597. doi:10.1016/j.cell.2016.05.082