NAM Journal embraces these recent advancements by serving as a hub for dissemination and worldwide exchange of information regarding state-of-the-art NAM developments. NAM Journal welcomes original research papers, review papers, opinion papers and meeting reports dealing with NAM production and their use in human toxicology, ecotoxicology, chemical risk assessment and biomedical research, amongst other fields. While focus is put on full replacement of animal experimentation, manuscripts that support other 3Rs principles, including reduction and refinement of animal experimentation, will also be considered when well justified. Manuscripts can address all elements of the NAM life cycle, from conceptual development to acceptance, implementation and application. NAM Journal is a 3I (international, interdisciplinary and intersectoral) journal and encourages submission from all relevant disciplines, ranging from natural, formal, life and applied sciences all up to social sciences and humanities. The NAM Journal target audience includes undergraduates to full professionals in academic, industrial and regulatory settings in any part of the world.