Respiratory system

Michelle Brand, Felix Ritzmann, Kathrin Kattler, et al. Biochemical and transcriptomic evaluation of a 3D lung organoid platform for pre-clinical testing of active substances targeting senescence. Respiratory Research. 2024;25:3. doi:10.1186/s12931-023-02636-7

Rahaf Issa, Neus Lozano, Kostas Kostarelos, Sandra Vranic. Functioning human lung organoids model pulmonary tissue response from carbon nanomaterial exposures. Nano Today. 2024;56:102254. doi:10.1016/j.nantod.2024.102254

Vivek S Patel, Khalid Amin, Adam Wahab, et al. Cryopreserved human precision-cut lung slices provide an immune competent pulmonary test system for “on-demand” use and long-term cultures. Toxicological Sciences. 2023;191(2):253-265. doi:10.1093/toxsci/kfac136

Elo Madissoon, Amanda J. Oliver, Vitalii Kleshchevnikov, et al. A spatially resolved atlas of the human lung characterizes a gland-associated immune niche. Nature Genetics. 2023;55(1):66-77. doi:10.1038/s41588-022-01243-4

Lisa Sikkema, Ciro Ramírez-Suástegui, Daniel C. Strobl, et al. An integrated cell atlas of the lung in health and disease. Nature Medicine. 2023;29(6):1563-1577. doi:10.1038/s41591-023-02327-2

Wenhao Yang, Yingna Li, Fang Shi, Hanmin Liu. Human lung organoid: Models for respiratory biology and diseases. Developmental Biology. 2023;494:26-34. doi:10.1016/j.ydbio.2022.12.001

Kyungtae Lim, Alex P. A. Donovan, Walfred Tang, et al. Organoid modeling of human fetal lung alveolar development reveals mechanisms of cell fate patterning and neonatal respiratory disease. Cell Stem Cell. 2023;30(1):20-37.e9. doi:10.1016/j.stem.2022.11.013

E. A. Rosado-Olivieri, B. Razooky, J. Le Pen, et al. Organotypic human lung bud microarrays identify BMP-dependent SARS-CoV-2 infection in lung cells. Stem Cell Reports. 2023;18(5):1107-1122. doi:10.1016/j.stemcr.2023.03.015

Artur C.G. da Silva, Marize C. Valadares. The Application of New Approach Methodologies in Respiratory Disease Research: Their Role in Improving Translational Medicine from Bench to Bedside. Alternatives to Laboratory Animals. 2023;51(3):161-174. doi:10.1177/02611929231170392

Tessa Hughes, Krijn K. Dijkstra, Emma L. Rawlins, Robert E. Hynds. Open questions in human lung organoid research. Frontiers in Pharmacology. 2023;13. https://www.frontiersin.org/articles/10.3389/fphar.2022.1083017.