Respiratory system

Rina Hashimoto, Junya Takahashi, Keisuke Shirakura, et al. SARS-CoV-2 disrupts respiratory vascular barriers by suppressing Claudin-5 expression. Science Advances. 2022;8(38):eabo6783. doi:10.1126/sciadv.abo6783

Flávia Viana, Cecilia M. O’Kane, Gunnar N. Schroeder. Precision-cut lung slices: A powerful ex vivo model to investigate respiratory infectious diseases. Molecular Microbiology. 2022;117(3):578-588. doi:10.1111/mmi.14817

Haiqing Bai, Donald E. Ingber. What Can an Organ-on-a-Chip Teach Us About Human Lung Pathophysiology?. Physiology. 2022;37(5):242-252. doi:10.1152/physiol.00012.2022

Julio Sempere, Suélen Andreia Rossi, Irene Chamorro-Herrero, et al. Minilungs from Human Embryonic Stem Cells to Study the Interaction of Streptococcus pneumoniae with the Respiratory Tract. Microbiology Spectrum. 2022;10(3):e0045322. doi:10.1128/spectrum.00453-22

Mabel Barreiro Carpio, Mohammadhossein Dabaghi, Julia Ungureanu, Martin R. Kolb, Jeremy A. Hirota, Jose Manuel Moran-Mirabal. 3D Bioprinting Strategies, Challenges, and Opportunities to Model the Lung Tissue Microenvironment and Its Function. Frontiers in Bioengineering and Biotechnology. 2021;9. https://www.frontiersin.org/articles/10.3389/fbioe.2021.773511.

Longlong Si, Haiqing Bai, Melissa Rodas, et al. A human-airway-on-a-chip for the rapid identification of candidate antiviral therapeutics and prophylactics. Nature Biomedical Engineering. 2021;5(8):815-829. doi:10.1038/s41551-021-00718-9

Pauline Zamprogno, Simon Wüthrich, Sven Achenbach, et al. Second-generation lung-on-a-chip with an array of stretchable alveoli made with a biological membrane. Communications Biology. 2021;4(1):1-10. doi:10.1038/s42003-021-01695-0

Jonas C. Schupp, Taylor S. Adams, Carlos Cosme, et al. Integrated Single-Cell Atlas of Endothelial Cells of the Human Lung. Circulation. 2021;144(4):286-302. doi:10.1161/CIRCULATIONAHA.120.052318

Kambez H. Benam, Richard Novak, Thomas C. Ferrante, Youngjae Choe, Donald E. Ingber. Biomimetic smoking robot for in vitro inhalation exposure compatible with microfluidic organ chips. Nature Protocols. 2020;15(2):183-206. doi:10.1038/s41596-019-0230-y

Stefanie Deinhardt-Emmer, Knut Rennert, Elisabeth Schicke, et al. Co-infection with Staphylococcus aureus after primary influenza virus infection leads to damage of the endothelium in a human alveolus-on-a-chip model. Biofabrication. 2020;12(2):025012. doi:10.1088/1758-5090/ab7073