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Rina Hashimoto, Junya Takahashi, Keisuke Shirakura, et al. SARS-CoV-2 disrupts respiratory vascular barriers by suppressing Claudin-5 expression. Science Advances. 2022;8(38):eabo6783. doi:10.1126/sciadv.abo6783
Immune/infectious disease
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Haiqing Bai, Longlong Si, Amanda Jiang, et al. Mechanical control of innate immune responses against viral infection revealed in a human lung alveolus chip. Nature Communications. 2022;13(1):1928. doi:10.1038/s41467-022-29562-4
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Girija Goyal, Pranav Prabhala, Gautam Mahajan, et al. Ectopic Lymphoid Follicle Formation and Human Seasonal Influenza Vaccination Responses Recapitulated in an Organ-on-a-Chip. Advanced Science. 2022;9(14):2103241. doi:10.1002/advs.202103241
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Merel Ritskes-Hoitinga, Yari Barella, Tineke Kleinhout-Vliek. The Promises of Speeding Up: Changes in Requirements for Animal Studies and Alternatives during COVID-19 Vaccine Approval–A Case Study. Animals. 2022;12(13):1735. doi:10.3390/ani12131735
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Emi Sano, Tatsuya Suzuki, Rina Hashimoto, et al. Cell response analysis in SARS-CoV-2 infected bronchial organoids. Communications Biology. 2022;5(1):1-9. doi:10.1038/s42003-022-03499-2
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Anna Kopenhagen, Isabell Ramming, Belinda Camp, et al. Streptococcus pneumoniae Affects Endothelial Cell Migration in Microfluidic Circulation. Frontiers in Microbiology. 2022;13:852036. doi:10.3389/fmicb.2022.852036
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Sandro Satta, Fahimeh Shahabipour, Wei Gao, et al. Engineering viral genomics and nano-liposomes in microfluidic platforms for patient-specific analysis of SARS-CoV-2 variants. Theranostics. 2022;12(10):4779-4790. doi:10.7150/thno.72339
1.
Kevin G. Chen, Kyeyoon Park, Jason R. Spence. Studying SARS-CoV-2 infectivity and therapeutic responses with complex organoids. Nature Cell Biology. 2021;23(8):822-833. doi:10.1038/s41556-021-00721-x
1.
Min Zhang, Peng Wang, Ronghua Luo, et al. Biomimetic Human Disease Model of SARS-CoV-2-Induced Lung Injury and Immune Responses on Organ Chip System. Advanced Science. 2021;8(3):2002928. doi:10.1002/advs.202002928
1.
Partho Protim Adhikary, Qurrat Ul Ain, Andreas Christian Hocke, Sarah Hedtrich. COVID-19 highlights the model dilemma in biomedical research. Nature Reviews Materials. 2021;6(5):374-376. doi:10.1038/s41578-021-00305-z