Gastrointestinal system

Jianbo Zhang, Yu-Ja Huang, Martin Trapecar, et al. An immune-competent human gut microphysiological system enables inflammation-modulation by Faecalibacterium prausnitzii. npj Biofilms and Microbiomes. 2024;10(1):1-11. doi:10.1038/s41522-024-00501-z

Jiandong Yang, Yoshikazu Hirai, Kei Iida, et al. Integrated-gut-liver-on-a-chip platform as an in vitro human model of non-alcoholic fatty liver disease. Communications Biology. 2023;6(1):1-14. doi:10.1038/s42003-023-04710-8

Changxiu Xian, Jiaxin Zhang, Suqing Zhao, Xiang-Guang Li. Gut-on-a-chip for disease models. Journal of Tissue Engineering. 2023;14:20417314221149882. doi:10.1177/20417314221149882

Vadim Osadchiy, Roshan Bal, Emeran A. Mayer, et al. Machine learning model to predict obesity using gut metabolite and brain microstructure data. Scientific Reports. 2023;13(1):5488. doi:10.1038/s41598-023-32713-2

Wyatt E. Lanik, Cliff J. Luke, Lila S. Nolan, et al. Microfluidic device facilitates in vitro modeling of human neonatal necrotizing enterocolitis–on-a-chip. JCI Insight. 2023;8(8):e146496. doi:10.1172/jci.insight.146496

Sunghee Estelle Park, Shawn Kang, Jungwook Paek, et al. Geometric engineering of organoid culture for enhanced organogenesis in a dish. Nature Methods. 2022;19(11):1449-1460. doi:10.1038/s41592-022-01643-8

Gui-Wei He, Lin Lin, Jeff DeMartino, et al. Optimized human intestinal organoid model reveals interleukin-22-dependency of paneth cell formation. Cell Stem Cell. 2022;29(9):1333-1345.e6. doi:10.1016/j.stem.2022.08.002

Claudia Günther, Beate Winner, Markus F. Neurath, Thaddeus S. Stappenbeck. Organoids in gastrointestinal diseases: from experimental models to clinical translation. Gut. 2022;71(9):1892-1908. doi:10.1136/gutjnl-2021-326560

Jens Puschhof, Cayetano Pleguezuelos-Manzano, Adriana Martinez-Silgado, et al. Intestinal organoid cocultures with microbes. Nature Protocols. 2021;16(10):4633-4649. doi:10.1038/s41596-021-00589-z

Jens Puschhof, Cayetano Pleguezuelos-Manzano, Hans Clevers. Organoids and organs-on-chips: Insights into human gut-microbe interactions. Cell Host & Microbe. 2021;29(6):867-878. doi:10.1016/j.chom.2021.04.002