Cardiovascular system

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Cristiane M. Franca, Maria Elisa Lima Verde, Alice Corrêa Silva-Sousa, et al. Perivascular cells function as key mediators of mechanical and structural changes in vascular capillaries. Science Advances. 2025;11(2):eadp3789. doi:10.1126/sciadv.adp3789
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M. Iveth Garcia, Keri Dame, Verena Charwat, et al. Human induced pluripotent stem cell-derived cardiomyocytes and their use in a cardiac organ-on-a-chip to assay electrophysiology, calcium and contractility. Nature Protocols. 2025:1-47. doi:10.1038/s41596-025-01166-4
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Ana Kojic, Javid Moslehi, Bonnie Ky, Joseph C. Wu. Cardiometabolic disease and cardio-oncology: Insights from iPSC models and tissue engineering. Cell Reports Medicine. 2025;6(9):102261. doi:10.1016/j.xcrm.2025.102261
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Chengyi Tu, Arianne Caudal, Yu Liu, Sanjiv M. Narayan, Joseph C. Wu. Modeling heart rhythm using human engineered heart tissues. Nature Protocols. 2025:1-24. doi:10.1038/s41596-025-01217-w
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Colin O’Hern, Sammantha Caywood, Shakhlo Aminova, et al. Human heart-macrophage assembloids mimic immune-cardiac interactions and enable arrhythmia disease modeling. Cell Stem Cell. 2025;32(11):1671-1690.e13. doi:10.1016/j.stem.2025.09.011
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Rohan Bhattacharya, Tarsha Ward, Titilola D. Kalejaiye, et al. Engineered human induced pluripotent stem cell models reveal altered podocytogenesis in congenital heart disease-associated SMAD2 mutations. Nature Biomedical Engineering. 2025:1-20. doi:10.1038/s41551-025-01543-0
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Aleksandra Kostina, Yonatan R. Lewis-Israeli, Mishref Abdelhamid, et al. ER stress and lipid imbalance drive diabetic embryonic cardiomyopathy in an organoid model of human heart development. Stem Cell Reports. 2024;19(3):317-330. doi:10.1016/j.stemcr.2024.01.003
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