Cardiovascular system

Roberta Visone, Ferran Lozano-Juan, Simona Marzorati, et al. Predicting human cardiac QT alterations and pro-arrhythmic effects of compounds with a 3D beating heart-on-chip platform. Toxicological Sciences. 2023;191(1):47-60. doi:10.1093/toxsci/kfac108

Yuhao Qiang, Abdoulaye Sissoko, Zixiang L. Liu, et al. Microfluidic study of retention and elimination of abnormal red blood cells by human spleen with implications for sickle cell disease. Proceedings of the National Academy of Sciences. 2023;120(6):e2217607120. doi:10.1073/pnas.2217607120

Justin Silberman, Jessica Boehlein, Talia Abbate, Erika Moore. A Biomaterial Model to Assess the Effects of Age in Vascularization. Cells Tissues Organs. 2023;212(1):74-83. doi:10.1159/000523859

Anoosha Khan, Priya Kumari, Naina Kumari, et al. Biomimetic Approaches in Cardiac Tissue Engineering: Replicating the Native Heart Microenvironment. Cureus. 2023;15(8):e43431. doi:10.7759/cureus.43431

Hanna Vuorenpää, Miina Björninen, Hannu Välimäki, et al. Building blocks of microphysiological system to model physiology and pathophysiology of human heart. Frontiers in Physiology. 2023;14:1213959. doi:10.3389/fphys.2023.1213959

Suji Choi, Keel Yong Lee, Sean L. Kim, et al. Fibre-infused gel scaffolds guide cardiomyocyte alignment in 3D-printed ventricles. Nature Materials. 2023;22(8):1039-1046. doi:10.1038/s41563-023-01611-3

Omar Mourad, Ryan Yee, Mengyuan Li, Sara S. Nunes. Modeling Heart Diseases on a Chip: Advantages and Future Opportunities. Circulation Research. 2023;132(4):483-497. doi:10.1161/CIRCRESAHA.122.321670

Anna B. Meier, Dorota Zawada, Maria Teresa De Angelis, et al. Epicardioid single-cell genomics uncovers principles of human epicardium biology in heart development and disease. Nature Biotechnology. 2023:1-14. doi:10.1038/s41587-023-01718-7

Tiannan Liu, Enno Klussmann. Targeting cAMP signaling compartments in iPSC-derived models of cardiovascular disease. Current Opinion in Pharmacology. 2023;71:102392. doi:10.1016/j.coph.2023.102392

Jordyn Folh, Renita E. Horton, Ralf Martz Sulague, Jacques Kpodonu. Heart-on-a-Chip: Leveraging Technology for Sickle Cell Disease. JACC: Advances. 2023;2(4):100355. doi:10.1016/j.jacadv.2023.100355