Stem-cell biotechnology

Xin Cui, Xinwei Li, Huimin Zheng, et al. Human midbrain organoids: a powerful tool for advanced Parkinson’s disease modeling and therapy exploration. npj Parkinson’s Disease. 2024;10(1):1-14. doi:10.1038/s41531-024-00799-8

Patricia R. Pitrez, Luis M. Monteiro, Oliver Borgogno, Xavier Nissan, Jerome Mertens, Lino Ferreira. Cellular reprogramming as a tool to model human aging in a dish. Nature Communications. 2024;15(1):1816. doi:10.1038/s41467-024-46004-5

Moritz Hofer, Maria A. Duque-Correa, Matthias P. Lutolf. Patterned gastrointestinal monolayers with bilateral access as observable models of parasite gut infection. Nature Biomedical Engineering. 2024:1-11. doi:10.1038/s41551-024-01313-4

Drew R. Neavin, Angela M. Steinmann, Nona Farbehi, et al. A village in a dish model system for population-scale hiPSC studies. Nature Communications. 2023;14(1):3240. doi:10.1038/s41467-023-38704-1

Kevin G. Chen, Kyeyoon Park, Jason R. Spence. Studying SARS-CoV-2 infectivity and therapeutic responses with complex organoids. Nature Cell Biology. 2021;23(8):822-833. doi:10.1038/s41556-021-00721-x

Joep Beumer, Maarten H. Geurts, Mart M. Lamers, et al. A CRISPR/Cas9 genetically engineered organoid biobank reveals essential host factors for coronaviruses. Nature Communications. 2021;12(1):5498. doi:10.1038/s41467-021-25729-7

Yi Zheng, Xufeng Xue, Yue Shao, et al. Controlled modelling of human epiblast and amnion development using stem cells. Nature. 2019;573(7774):421-425. doi:10.1038/s41586-019-1535-2

Magdalena Kasendra, Alessio Tovaglieri, Alexandra Sontheimer-Phelps, et al. Development of a primary human Small Intestine-on-a-Chip using biopsy-derived organoids. Scientific Reports. 2018;8(1):2871. doi:10.1038/s41598-018-21201-7