Research Design

Vijay Pal Singh, Kunal Pratap, Juhi Sinha, Koundinya Desiraju, Devika Bahal, Ritushree Kukreti. Critical evaluation of challenges and future use of animals in experimentation for biomedical research. International Journal of Immunopathology and Pharmacology. 2016;29(4):551-561. doi:10.1177/0394632016671728

Susan Bridgwood Green. Can animal data translate to innovations necessary for a new era of patient-centred and individualised healthcare? Bias in preclinical animal research. BMC Medical Ethics. 2015;16:53. doi:10.1186/s12910-015-0043-7

Jennifer A. Hirst, Jeremy Howick, Jeffrey K. Aronson, et al. The need for randomization in animal trials: an overview of systematic reviews. PloS One. 2014;9(6):e98856. doi:10.1371/journal.pone.0098856

Valerie C. Henderson, Jonathan Kimmelman, Dean Fergusson, Jeremy M. Grimshaw, Dan G. Hackam. Threats to validity in the design and conduct of preclinical efficacy studies: a systematic review of guidelines for in vivo animal experiments. PLoS Medicine. 2013;10(7):e1001489. doi:10.1371/journal.pmed.1001489

Pablo Perel, Ian Roberts, Emily Sena, et al. Comparison of treatment effects between animal experiments and clinical trials: systematic review. BMJ. 2007;334:197. doi:10.1136/bmj.39048.407928.BE

Victoria E. O’Collins, Malcolm R. Macleod, Geoffrey A. Donnan, Laura L. Horky, Bart H. van der Worp, David W. Howells. 1,026 experimental treatments in acute stroke. Annals of Neurology. 2006;59(3):467-477. doi:10.1002/ana.20741

John P. A. Ioannidis. Why Most Published Research Findings Are False. PLOS Medicine. 2(8):e124. doi:10.1371/journal.pmed.0020124

David Moher, Lex Bouter, Sabine Kleinert, et al. The Hong Kong Principles for assessing researchers: Fostering research integrity. PLOS Biology. 18(7):e3000737. doi:10.1371/journal.pbio.3000737

Harriet A. Carroll, Zoi Toumpakari, Laura Johnson, James A. Betts. The perceived feasibility of methods to reduce publication bias. PLOS ONE. 12(10):e0186472. doi:10.1371/journal.pone.0186472