Precision Medicine

Valentina Paloschi, Maria Sabater-Lleal, Heleen Middelkamp, et al. Organ-on-a-chip technology: a novel approach to investigate cardiovascular diseases. Cardiovascular Research. 2021;117(14):2742-2754. doi:10.1093/cvr/cvab088

Jens Puschhof, Cayetano Pleguezuelos-Manzano, Hans Clevers. Organoids and organs-on-chips: Insights into human gut-microbe interactions. Cell Host & Microbe. 2021;29(6):867-878. doi:10.1016/j.chom.2021.04.002

Kanako Yuki, Ning Cheng, Michitaka Nakano, Calvin J. Kuo. Organoid Models of Tumor Immunology. Trends in Immunology. 2020;41(8):652-664. doi:10.1016/j.it.2020.06.010

Else Driehuis, Kai Kretzschmar, Hans Clevers. Establishment of patient-derived cancer organoids for drug-screening applications. Nature Protocols. 2020;15(10):3380-3409. doi:10.1038/s41596-020-0379-4

David Tuveson, Hans Clevers. Cancer modeling meets human organoid technology. Science (New York, N.Y.). 2019;364(6444):952-955. doi:10.1126/science.aaw6985

Norman Sachs, Joep de Ligt, Oded Kopper, et al. A Living Biobank of Breast Cancer Organoids Captures Disease Heterogeneity. Cell. 2018;172(1-2):373-386.e10. doi:10.1016/j.cell.2017.11.010

Shurong Hou, Hervé Tiriac, Banu Priya Sridharan, et al. Advanced Development of Primary Pancreatic Organoid Tumor Models for High-Throughput Phenotypic Drug Screening. SLAS discovery: advancing life sciences R & D. 2018;23(6):574-584. doi:10.1177/2472555218766842

Kacey Ronaldson-Bouchard, Gordana Vunjak-Novakovic. Organs-on-a-Chip: A Fast Track for Engineered Human Tissues in Drug Development. Cell Stem Cell. 2018;22(3):310-324. doi:10.1016/j.stem.2018.02.011

Norman Sachs, Joep de Ligt, Oded Kopper, et al. A Living Biobank of Breast Cancer Organoids Captures Disease Heterogeneity. Cell. 2018;172(1-2):373-386.e10. doi:10.1016/j.cell.2017.11.010

A. S. Khazali, A. M. Clark, A. Wells. A Pathway to Personalizing Therapy for Metastases Using Liver-on-a-Chip Platforms. Stem Cell Reviews and Reports. 2017;13(3):364-380. doi:10.1007/s12015-017-9735-3