inflammatory bowel disease

Thomas W. Dennison, Rachel D. Edgar, Felicity Payne, et al. Patient-derived organoid biobank identifies epigenetic dysregulation of intestinal epithelial MHC-I as a novel mechanism in severe Crohn’s Disease. Gut. 2024;73:1464-1477. doi:10.1136/gutjnl-2024-332043

Changxiu Xian, Jiaxin Zhang, Suqing Zhao, Xiang-Guang Li. Gut-on-a-chip for disease models. Journal of Tissue Engineering. 2023;14:20417314221149882. doi:10.1177/20417314221149882

Gui-Wei He, Lin Lin, Jeff DeMartino, et al. Optimized human intestinal organoid model reveals interleukin-22-dependency of paneth cell formation. Cell Stem Cell. 2022;29(9):1333-1345.e6. doi:10.1016/j.stem.2022.08.002