Genetic engineering

Laura Rüland, Francesco Andreatta, Simone Massalini, et al. Organoid models of fibrolamellar carcinoma mutations reveal hepatocyte transdifferentiation through cooperative BAP1 and PRKAR2A loss. Nature Communications. 2023;14(1):2377. doi:10.1038/s41467-023-37951-6

Joep Beumer, Maarten H. Geurts, Mart M. Lamers, et al. A CRISPR/Cas9 genetically engineered organoid biobank reveals essential host factors for coronaviruses. Nature Communications. 2021;12(1):5498. doi:10.1038/s41467-021-25729-7