Drug Discovery

1.
Valentina Paloschi, Maria Sabater-Lleal, Heleen Middelkamp, et al. Organ-on-a-chip technology: a novel approach to investigate cardiovascular diseases. Cardiovascular Research. 2021;117(14):2742-2754. doi:10.1093/cvr/cvab088
View Full Reference
1.
Smriti Mallapaty. The mini lungs and other organoids helping to beat COVID. Nature. 2021;593(7860):492-494. doi:10.1038/d41586-021-01395-z
View Full Reference
1.
Alice Maria Giani, Shuibing Chen. Human pluripotent stem cell-based organoids and cell platforms for modelling SARS-CoV-2 infection and drug discovery. Stem Cell Research. 2021;53:102207. doi:10.1016/j.scr.2021.102207
View Full Reference
1.
Rachel E. Young, Dan Dongeun Huh. Organ-on-a-chip technology for the study of the female reproductive system. Advanced Drug Delivery Reviews. 2021;173:461-478. doi:10.1016/j.addr.2021.03.010
View Full Reference
1.
Lorna Ewart, Adrian Roth. Opportunities and challenges with microphysiological systems: a pharma end-user perspective. Nature Reviews. Drug Discovery. 2021;20(5):327-328. doi:10.1038/d41573-020-00030-2
View Full Reference
1.
Patrick M. Misun, Burçak Yesildag, Felix Forschler, et al. In Vitro Platform for Studying Human Insulin Release Dynamics of Single Pancreatic Islet Microtissues at High Resolution. Advanced Biosystems. 2020;4(3):e1900291. doi:10.1002/adbi.201900291
View Full Reference
1.
Jun-Hwan Yoo, Mark Donowitz. Intestinal enteroids/organoids: A novel platform for drug discovery in inflammatory bowel diseases. World Journal of Gastroenterology. 2019;25(30):4125-4147. doi:10.3748/wjg.v25.i30.4125
View Full Reference
1.
Ben G. Fitzpatrick, Elena Koustova, Yun Wang. Getting personal with the “reproducibility crisis”: interviews in the animal research community. Lab Animal. 2018;47(7):175-177. doi:10.1038/s41684-018-0088-6
View Full Reference
1.
Janet Piñero, Laura I. Furlong, Ferran Sanz. In silico models in drug development: where we are. Current Opinion in Pharmacology. 2018;42:111-121. doi:10.1016/j.coph.2018.08.007
View Full Reference
1.
A. Jain, R. Barrile, A. D. van der Meer, et al. Primary Human Lung Alveolus-on-a-chip Model of Intravascular Thrombosis for Assessment of Therapeutics. Clinical Pharmacology and Therapeutics. 2018;103(2):332-340. doi:10.1002/cpt.742
View Full Reference