Animals

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Melody Mills, Mary K. Estes. Physiologically relevant human tissue models for infectious diseases. Drug Discovery Today. 2016;21(9):1540-1552. doi:10.1016/j.drudis.2016.06.020
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Hans Clevers. Modeling Development and Disease with Organoids. Cell. 2016;165(7):1586-1597. doi:10.1016/j.cell.2016.05.082
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Vijay Pal Singh, Kunal Pratap, Juhi Sinha, Koundinya Desiraju, Devika Bahal, Ritushree Kukreti. Critical evaluation of challenges and future use of animals in experimentation for biomedical research. International Journal of Immunopathology and Pharmacology. 2016;29(4):551-561. doi:10.1177/0394632016671728
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Jarrod Bailey, Michelle Thew, Michael Balls. Predicting human drug toxicity and safety via animal tests: can any one species predict drug toxicity in any other, and do monkeys help?. Alternatives to laboratory animals: ATLA. 2015;43(6):393-403. doi:10.1177/026119291504300607
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Susan Bridgwood Green. Can animal data translate to innovations necessary for a new era of patient-centred and individualised healthcare? Bias in preclinical animal research. BMC Medical Ethics. 2015;16:53. doi:10.1186/s12910-015-0043-7
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Jarrod Bailey, Michelle Thew, Michael Balls. An analysis of the use of animal models in predicting human toxicology and drug safety. Alternatives to Laboratory Animals. 2014;42(3):181-199. doi:10.1177/026119291404200306
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Jennifer A. Hirst, Jeremy Howick, Jeffrey K. Aronson, et al. The need for randomization in animal trials: an overview of systematic reviews. PloS One. 2014;9(6):e98856. doi:10.1371/journal.pone.0098856
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Jarrod Bailey. Monkey-based research on human disease: the implications of genetic differences. Alternatives to Laboratory Animals. 2014;42(5):287-317. doi:10.1177/026119291404200504
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Valerie C. Henderson, Jonathan Kimmelman, Dean Fergusson, Jeremy M. Grimshaw, Dan G. Hackam. Threats to validity in the design and conduct of preclinical efficacy studies: a systematic review of guidelines for in vivo animal experiments. PLoS Medicine. 2013;10(7):e1001489. doi:10.1371/journal.pmed.1001489
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Dongeun Huh, Daniel C. Leslie, Benjamin D. Matthews, et al. A human disease model of drug toxicity-induced pulmonary edema in a lung-on-a-chip microdevice. Science Translational Medicine. 2012;4(159). doi:10.1126/scitranslmed.3004249
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