Translation and validation

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Donald E. Ingber. Is it Time for Reviewer 3 to Request Human Organ Chip Experiments Instead of Animal Validation Studies?. Advanced Science. 2020;7(22):2002030. doi:10.1002/advs.202002030
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Olivier J. Wouters, Martin McKee, Jeroen Luyten. Estimated Research and Development Investment Needed to Bring a New Medicine to Market, 2009-2018. JAMA. 2020;323(9):844-853. doi:10.1001/jama.2020.1166
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Francesca Pistollato, Camilla Bernasconi, Janine McCarthy, et al. Alzheimer’s Disease, and Breast and Prostate Cancer Research: Translational Failures and the Importance to Monitor Outputs and Impact of Funded Research. Animals (Basel). 2020;10(7):1194. doi:10.3390/ani10071194
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Jarrod Bailey, Michael Balls. Clinical impact of high-profile animal-based research reported in the UK national press. BMJ Open Science. 2020;4(1):e100039. doi:10.1136/bmjos-2019-100039
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S. Vincent Rajkumar. The high cost of prescription drugs: causes and solutions. Blood Cancer Journal. 2020;10(6):71. doi:10.1038/s41408-020-0338-x
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Merel Ritskes-Hoitinga, Cathalijn Leenaars, Wouter Beumer, Tineke Coenen-de Roo, Frans Stafleu, Franck L. B. Meijboom. Improving Translation by Identifying Evidence for More Human-Relevant Preclinical Strategies. Animals: an open access journal from MDPI. 2020;10(7):1170. doi:10.3390/ani10071170
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Nora Franzen, Wim H. van Harten, Valesca P. Retèl, Peter Loskill, Janny van den Eijnden-van Raaij, Maarten IJzerman. Impact of organ-on-a-chip technology on pharmaceutical R&D costs. Drug Discovery Today. 2019;24(9):1720-1724. doi:10.1016/j.drudis.2019.06.003
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Gail A. Van Norman. Limitations of Animal Studies for Predicting Toxicity in Clinical Trials: Is it Time to Rethink Our Current Approach?. JACC. Basic to translational science. 2019;4(7):845-854. doi:10.1016/j.jacbts.2019.10.008
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John J. Pippin, Sarah E. Cavanaugh, Francesca Pistollato. Animal Research for Alzheimer Disease: Failures of Science and Ethics. In: Kathrin Herrmann, Kimberley Jayne, eds. Animal Experimentation: Working Towards a Paradigm Change. Brill; 2019:480-516. https://www.jstor.org/stable/10.1163/j.ctvjhzq0f.27.
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John P. Gluck. Afterword: Evidence over Interests. In: Kathrin Herrmann, Kimberley Jayne, eds. Animal Experimentation. Brill; 2019:689-691. https://www.jstor.org/stable/10.1163/j.ctvjhzq0f.36.
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