Translation and validation

Bonnie L. Hylander, Elizabeth A. Repasky, Sandra Sexton. Using Mice to Model Human Disease: Understanding the Roles of Baseline Housing-Induced and Experimentally Imposed Stresses in Animal Welfare and Experimental Reproducibility. Animals. 2022;12(3):371. doi:10.3390/ani12030371

Jack W. Scannell, James Bosley, John A. Hickman, et al. Predictive validity in drug discovery: what it is, why it matters and how to improve it. Nature Reviews Drug Discovery. 2022;21(12):915-931. doi:10.1038/s41573-022-00552-x

Tracy D. Zhang, Scott C. Kolbe, Leah C. Beauchamp, Ella K. Woodbridge, David I. Finkelstein, Emma L. Burrows. How Well Do Rodent Models of Parkinson’s Disease Recapitulate Early Non-Motor Phenotypes? A Systematic Review. Biomedicines. 2022;10(12):3026. doi:10.3390/biomedicines10123026

Laura Gribaldo, Adelaide Dura. EURL ECVAM Literature Review Series on Advanced Non-Animal Models for Respiratory Diseases, Breast Cancer and Neurodegenerative Disorders. Animals (Basel). 2022;12(17):2180. doi:10.3390/ani12172180

Jessica Cait, Alissa Cait, R. Wilder Scott, Charlotte B. Winder, Georgia J. Mason. Conventional laboratory housing increases morbidity and mortality in research rodents: results of a meta-analysis. BMC Biology. 2022;20(1):15. doi:10.1186/s12915-021-01184-0

Mathias Busek, Aleksandra Aizenshtadt, Mikel Amirola-Martinez, Ludivine Delon, Stefan Krauss. Academic User View: Organ-on-a-Chip Technology. Biosensors. 2022;12(2):126. doi:10.3390/bios12020126

Lorenzo Del Pace, Laura Viviani, Marco Straccia. Researchers and Their Experimental Models: A Pilot Survey in the Context of the European Union Health and Life Science Research. Animals. 2022;12(20):2778. doi:10.3390/ani12202778

Passley Hargrove-Grimes, Lucie A. Low, Danilo A. Tagle. Microphysiological Systems: Stakeholder Challenges to Adoption in Drug Development. Cells Tissues Organs. 2022;211(3):269-281. doi:10.1159/000517422

Nikolaos G. Frangogiannis. Why animal model studies are lost in translation. The Journal of Cardiovascular Aging. 2022;2(22). doi:10.20517/jca.2022.10

Lorna Ewart, Athanasia Apostolou, Skyler A. Briggs, et al. Performance assessment and economic analysis of a human Liver-Chip for predictive toxicology. Communications Medicine. 2022;2:154. doi:10.1038/s43856-022-00209-1