Nervous system

Xianwei Chen, Guoqiang Sun, E Tian, et al. Modeling Sporadic Alzheimer’s Disease in Human Brain Organoids under Serum Exposure. Advanced Science. 2021;8(18):2101462. doi:10.1002/advs.202101462

Foluwasomi A. Oyefeso, Alysson R. Muotri, Christopher G. Wilson, Michael J. Pecaut. Brain organoids: A promising model to assess oxidative stress-induced central nervous system damage. Developmental Neurobiology. 2021;81(5):653-670. doi:10.1002/dneu.22828

Florencia D. Haase, Bronte Coorey, Lisa Riley, Laurence C. Cantrill, Patrick P. L. Tam, Wendy A. Gold. Pre-clinical Investigation of Rett Syndrome Using Human Stem Cell-Based Disease Models. Frontiers in Neuroscience. 2021;15. https://www.frontiersin.org/articles/10.3389/fnins.2021.698812.

Jonas Simon Fleck, Fátima Sanchís-Calleja, Zhisong He, et al. Resolving organoid brain region identities by mapping single-cell genomic data to reference atlases. Cell Stem Cell. 2021;28(6):1177-1180. doi:10.1016/j.stem.2021.03.015

Zhonglin Lyu, Jon Park, Kwang-Min Kim, et al. A neurovascular-unit-on-a-chip for the evaluation of the restorative potential of stem cell therapies for ischaemic stroke. Nature Biomedical Engineering. 2021;5(8):847-863. doi:10.1038/s41551-021-00744-7

Nienke R. Wevers, Arya Lekshmi Nair, Tania M. Fowke, et al. Modeling ischemic stroke in a triculture neurovascular unit on-a-chip. Fluids and Barriers of the CNS. 2021;18:59. doi:10.1186/s12987-021-00294-9

Cameron S. Cowan, Magdalena Renner, Martina De Gennaro, et al. Cell Types of the Human Retina and Its Organoids at Single-Cell Resolution. Cell. 2020;182(6):1623-1640.e34. doi:10.1016/j.cell.2020.08.013

Goodwell Nzou, Robert T. Wicks, Nicole R. VanOstrand, et al. Multicellular 3D Neurovascular Unit Model for Assessing Hypoxia and Neuroinflammation Induced Blood-Brain Barrier Dysfunction. Scientific Reports. 2020;10:9766. doi:10.1038/s41598-020-66487-8

Sabina Kanton, Michael James Boyle, Zhisong He, et al. Organoid single-cell genomic atlas uncovers human-specific features of brain development. Nature. 2019;574(7778):418-422. doi:10.1038/s41586-019-1654-9

Richard Lieberman, Henry R. Kranzler, Eric S. Levine, Jonathan Covault. Examining the effects of alcohol on GABAA receptor mRNA expression and function in neural cultures generated from control and alcohol dependent donor induced pluripotent stem cells. Alcohol. 2018;66:45-53. doi:10.1016/j.alcohol.2017.08.005