Nervous system

Isabel Rosety, Alise Zagare, Claudia Saraiva, et al. Impaired neuron differentiation in GBA-associated Parkinson’s disease is linked to cell cycle defects in organoids. npj Parkinson’s Disease. 2023;9:166. doi:10.1038/s41531-023-00616-8

Michel H. Y. Hu, Jean-Philippe Frimat, Kim Rijkers, et al. Spontaneous Epileptic Recordings from hiPSC-Derived Cortical Neurons Cultured with a Human Epileptic Brain Biopsy on a Multi Electrode Array. Applied Sciences. 2023;13(3):1432. doi:10.3390/app13031432

Jacqueline A. Tickle, Jon Sen, Christopher Adams, et al. A benchtop brain injury model using resected donor tissue from patients with Chiari malformation. Neural Regeneration Research. 2023;18(5):1057. doi:10.4103/1673-5374.355761

Chong Li, Jonas Simon Fleck, Catarina Martins-Costa, et al. Single-cell brain organoid screening identifies developmental defects in autism. Nature. 2023;621(7978):373-380. doi:10.1038/s41586-023-06473-y

Daniel Reumann, Christian Krauditsch, Maria Novatchkova, et al. In vitro modeling of the human dopaminergic system using spatially arranged ventral midbrain–striatum–cortex assembloids. Nature Methods. 2023;20:2034-2047. doi:10.1038/s41592-023-02080-x

Paula Barreras, David Pamies, Thomas Hartung, Carlos A. Pardo. Human brain microphysiological systems in the study of neuroinfectious disorders. Experimental Neurology. 2023;365:114409. doi:10.1016/j.expneurol.2023.114409

Jonas Simon Fleck, Sophie Martina Johanna Jansen, Damian Wollny, et al. Inferring and perturbing cell fate regulomes in human brain organoids. Nature. 2023;621(7978):365-372. doi:10.1038/s41586-022-05279-8

Nicolas Daviaud, Eric Chen, Tara Edwards, Saud A. Sadiq. Cerebral organoids in primary progressive multiple sclerosis reveal stem cell and oligodendrocyte differentiation defect. Biology Open. 2023;12(3):bio059845. doi:10.1242/bio.059845

Philipp Wahle, Giovanna Brancati, Christoph Harmel, et al. Multimodal spatiotemporal phenotyping of human retinal organoid development. Nature Biotechnology. 2023. doi:10.1038/s41587-023-01747-2

Itzy E. Morales Pantoja, Lixuan Ding, Paulo E. C. Leite, et al. A Novel Approach to Increase Glial Cell Populations in Brain Microphysiological Systems. Advanced Biology. 2023:2300198. doi:10.1002/adbi.202300198