Nervous system

Eric Courchesne, Vani Taluja, Sanaz Nazari, et al. Embryonic origin of two ASD subtypes of social symptom severity: the larger the brain cortical organoid size, the more severe the social symptoms. Molecular Autism. 2024;15(1):22. doi:10.1186/s13229-024-00602-8

Mohammed R. Shaker, Andrii Slonchak, Bahaa Al-mhanawi, et al. Choroid plexus defects in Down syndrome brain organoids enhance neurotropism of SARS-CoV-2. Science Advances. 2024;10(23):eadj4735. doi:10.1126/sciadv.adj4735

Feline W. Lindhout, Fenna M. Krienen, Katherine S. Pollard, Madeline A. Lancaster. A molecular and cellular perspective on human brain evolution and tempo. Nature. 2024;630(8017):596-608. doi:10.1038/s41586-024-07521-x

Tyler J. Wenzel, Darrell D. Mousseau. Brain organoids engineered to give rise to glia and neural networks after 90 days in culture exhibit human-specific proteoforms. Frontiers in Cellular Neuroscience. 2024;18. doi:10.3389/fncel.2024.1383688

Chengyu Deng, Sean Whalen, Marilyn Steyert, et al. Massively parallel characterization of regulatory elements in the developing human cortex. Science. 2024;384(6698):eadh0559. doi:10.1126/science.adh0559

Louise A. Huuki-Myers, Abby Spangler, Nicholas J. Eagles, et al. A data-driven single-cell and spatial transcriptomic map of the human prefrontal cortex. Science. 2024;384(6698):eadh1938. doi:10.1126/science.adh1938

Soraya O. Sandoval, Gerarda Cappuccio, Karina Kruth, et al. Rigor and reproducibility in human brain organoid research: Where we are and where we need to go. Stem Cell Reports. 2024;19(6):796-816. doi:10.1016/j.stemcr.2024.04.008

Dennis M. Nahon, Marc Vila Cuenca, Francijna E. van den Hil, et al. Self-assembling 3D vessel-on-chip model with hiPSC-derived astrocytes. Stem Cell Reports. 2024;19(7):946-956. doi:10.1016/j.stemcr.2024.05.006

Diana Tavares Ferreira, Breanna Q. Shen, Juliet M. Mwirigi, et al. Deciphering the Molecular Landscape of Human Peripheral Nerves: Implications for Diabetic Peripheral Neuropathy.; 2024. doi:10.1101/2024.06.15.599167

Etta Carricaburu, Orion Benner, Scott R. Burlingham, et al. Gephyrin promotes autonomous assembly and synaptic localization of GABAergic postsynaptic components without presynaptic GABA release. Proceedings of the National Academy of Sciences. 2024;121(26):e2315100121. doi:10.1073/pnas.2315100121