Immune/infectious disease

Ruochen Zang, Maria Florencia Gomez Castro, Broc T. McCune, et al. TMPRSS2 and TMPRSS4 promote SARS-CoV-2 infection of human small intestinal enterocytes. Science Immunology. 2020;5(47):eabc3582. doi:10.1126/sciimmunol.abc3582

Jie Zhou, Cun Li, Xiaojuan Liu, et al. Infection of bat and human intestinal organoids by SARS-CoV-2. Nature Medicine. 2020;26(7):1077-1083. doi:10.1038/s41591-020-0912-6

Hiroaki Katsura, Vishwaraj Sontake, Aleksandra Tata, et al. Human Lung Stem Cell-Based Alveolospheres Provide Insights into SARS-CoV-2-Mediated Interferon Responses and Pneumocyte Dysfunction. Cell Stem Cell. 2020;27(6):890-904.e8. doi:10.1016/j.stem.2020.10.005

Yotam E. Bar-Ephraim, Kai Kretzschmar, Hans Clevers. Organoids in immunological research. Nature Reviews. Immunology. 2020;20(5):279-293. doi:10.1038/s41577-019-0248-y

Arun Sharma, Gustavo Garcia, Yizhou Wang, et al. Human iPSC-Derived Cardiomyocytes Are Susceptible to SARS-CoV-2 Infection. Cell Reports. Medicine. 2020;1(4):100052. doi:10.1016/j.xcrm.2020.100052

Grégory Seumois, Ciro Ramírez-Suástegui, Benjamin J. Schmiedel, et al. Single-cell transcriptomic analysis of allergen-specific T cells in allergy and asthma. Science Immunology. 2020;5(48):eaba6087. doi:10.1126/sciimmunol.aba6087

Zhongmin Tang, Na Kong, Xingcai Zhang, et al. A materials-science perspective on tackling COVID-19. Nature Reviews Materials. 2020;5(11):847-860. doi:10.1038/s41578-020-00247-y

Janna C. Nawroth, Carolina Lucchesi, Deion Cheng, et al. A Microengineered Airway Lung Chip Models Key Features of Viral-induced Exacerbation of Asthma. American Journal of Respiratory Cell and Molecular Biology. 2020;63(5):591-600. doi:10.1165/rcmb.2020-0010MA

Vanessa Monteil, Hyesoo Kwon, Patricia Prado, et al. Inhibition of SARS-CoV-2 Infections in Engineered Human Tissues Using Clinical-Grade Soluble Human ACE2. Cell. 2020;181(4):905-913.e7. doi:10.1016/j.cell.2020.04.004

Holly Ryan, Chelsey S. Simmons. Potential Applications of Microfluidics to Acute Kidney Injury Associated with Viral Infection. Cellular and Molecular Bioengineering. 2020;13(4):305-311. doi:10.1007/s12195-020-00649-6