Immune/infectious disease

Andrea I. Boyd, Leah A. Kafer, Isabel F. Escapa, et al. Nasal microbionts differentially colonize and elicit cytokines in human nasal epithelial organoids. mSphere. 2025;10(10):e00493-25. doi:10.1128/msphere.00493-25

Titilola D. Kalejaiye, Rohan Bhattacharya, Samira Musah. A Vascularized Human Organ Chip Reveals SARS-CoV-2 Susceptibility in Developmentally Guided Tissue Maturation. Cellular and Molecular Bioengineering. 2025. doi:10.1007/s12195-025-00851-4

Xin Chen, Mustafa Ghanizada, Vamsee Mallajosyula, et al. Differential roles of human CD4+ and CD8+ regulatory T cells in controlling self-reactive immune responses. Nature Immunology. 2025:1-10. doi:10.1038/s41590-024-02062-x

Jia Shang, Mei Yan, Hengning Ke. Advances and Global Trends in Three-Dimensional Human Tissue Models for HIV Research: A Bibliometric Analysis. Tissue Engineering Part B: Reviews. 2025:19373368251406871. doi:10.1177/19373368251406871

Angelica Medina, Yu-Chi Chen, Jiajing Zhang, et al. Modeling neurotropic virus infection with functional human neural spheroids as a platform for high-throughput antiviral screening and pathogenesis. Antiviral Research. 2025;242:106248. doi:10.1016/j.antiviral.2025.106248

Isabel Schultz-Pernice, Amal Fahmi, Francisco Brito, et al. Monkeypox virus spreads from cell-to-cell and leads to neuronal death in human neural organoids. Nature Communications. 2025;16(1):5376. doi:10.1038/s41467-025-61134-0

Rory K. M. Long, François Korbmacher, Paolo Ronchi, et al. Plasmodium falciparum impairs Ang-1 secretion by pericytes in a 3D brain microvessel model. EMBO Molecular Medicine. 2025;17(11):3110-3138. doi:10.1038/s44321-025-00319-y

Keitaro Kanie, Takeshi Ito, Genzo Iguchi, et al. Modeling of T cell-mediated autoimmune pituitary disease using human induced pluripotent stem cell-originated organoid. Nature Communications. 2025;16(1):7900. doi:10.1038/s41467-025-63183-x

James Nyirenda, Olympia M. Hardy, João Da Silva Filho, et al. Spatially resolved single-cell atlas unveils a distinct cellular signature of fatal lung COVID-19 in a Malawian population. Nature Medicine. 2024:1-13. doi:10.1038/s41591-024-03354-3

Cun Li, Yifei Yu, Zhixin Wan, et al. Human respiratory organoids sustained reproducible propagation of human rhinovirus C and elucidation of virus-host interaction. Nature Communications. 2024;15(1):10772. doi:10.1038/s41467-024-55076-2