Immune/infectious disease

James I. Kennedy, Scott P. Davies, Peter W. Hewett, et al. Organ-on-a-chip for studying immune cell adhesion to liver sinusoidal endothelial cells: the potential for testing immunotherapies and cell therapy trafficking. Frontiers in Cell and Developmental Biology. 2024;12. doi:10.3389/fcell.2024.1359451

Elena Morrocchi, Simon van Haren, Paolo Palma, Ofer Levy. Modeling human immune responses to vaccination in vitro. Trends in Immunology. 2024;45(1):32-47. doi:10.1016/j.it.2023.11.002

Sandra L. Leibel, Rachael N. McVicar, Rabi Murad, et al. A therapy for suppressing canonical and noncanonical SARS-CoV-2 viral entry and an intrinsic intrapulmonary inflammatory response. Proceedings of the National Academy of Sciences. 2024;121(30):e2408109121. doi:10.1073/pnas.2408109121

Marius F. Harter, Timothy Recaldin, Regine Gerard, et al. Analysis of off-tumour toxicities of T-cell-engaging bispecific antibodies via donor-matched intestinal organoids and tumouroids. Nature Biomedical Engineering. 2024;8:345-360. doi:10.1038/s41551-023-01156-5

Paula Barreras, David Pamies, Thomas Hartung, Carlos A. Pardo. Human brain microphysiological systems in the study of neuroinfectious disorders. Experimental Neurology. 2023;365:114409. doi:10.1016/j.expneurol.2023.114409

Kyeong Seob Hwang, Eun U Seo, Nakwon Choi, Jongbaeg Kim, Hong Nam Kim. 3D engineered tissue models for studying human-specific infectious viral diseases. Bioactive Materials. 2023;21:576-594. doi:10.1016/j.bioactmat.2022.09.010

Robert Jordan, Stephanie L Ford-Scheimer, Rodolfo M Alarcon, et al. Report of the Assay Guidance Workshop on 3-Dimensional Tissue Models for Antiviral Drug Development. The Journal of Infectious Diseases. 2023:jiad334. doi:10.1093/infdis/jiad334

Clare L. Thompson, Timothy Hopkins, Catrin Bevan, Hazel R. C. Screen, Karina T. Wright, Martin M. Knight. Human vascularised synovium-on-a-chip: a mechanically stimulated, microfluidic model to investigate synovial inflammation and monocyte recruitment. Biomedical Materials. 2023;18(6):065013. doi:10.1088/1748-605X/acf976

Pengfei Li, Spyridon T. Pachis, Guige Xu, et al. Mpox virus infection and drug treatment modelled in human skin organoids. Nature Microbiology. 2023:1-13. doi:10.1038/s41564-023-01489-6

Fuki Yokoi, Sayaka Deguchi, Kazuo Takayama. Organ-on-a-chip models for elucidating the cellular biology of infectious diseases. Biochimica Et Biophysica Acta. Molecular Cell Research. 2023;1870(6):119504. doi:10.1016/j.bbamcr.2023.119504