Cancer

Shengli Ding, Carolyn Hsu, Zhaohui Wang, et al. Patient-derived micro-organospheres enable clinical precision oncology. Cell Stem Cell. 2022;29(6):905-917.e6. doi:10.1016/j.stem.2022.04.006

Martina Crippa, Giuseppe Talò, Anaïs Lamouline, et al. A microfluidic model of human vascularized breast cancer metastasis to bone for the study of neutrophil-cancer cell interactions. Materials Today. Bio. 2022;17:100460. doi:10.1016/j.mtbio.2022.100460

Muhammad R. Haque, Caitlin R. Wessel, Daniel D. Leary, Chengyao Wang, Abhinav Bhushan, Faraz Bishehsari. Patient-derived pancreatic cancer-on-a-chip recapitulates the tumor microenvironment. Microsystems & Nanoengineering. 2022;8:36. doi:10.1038/s41378-022-00370-6

Francisco Conceição, Daniela M. Sousa, Joshua Loessberg-Zahl, et al. A metastasis-on-a-chip approach to explore the sympathetic modulation of breast cancer bone metastasis. Materials Today. Bio. 2022;13:100219. doi:10.1016/j.mtbio.2022.100219

Johannes Dornhof, Jochen Kieninger, Harshini Muralidharan, Jochen Maurer, Gerald A. Urban, Andreas Weltin. Microfluidic organ-on-chip system for multi-analyte monitoring of metabolites in 3D cell cultures. Lab on a Chip. 2022;22(2):225-239. doi:10.1039/D1LC00689D

Gabrielle Wishart, Priyanka Gupta, Andrew Nisbet, Giuseppe Schettino, Eirini Velliou. On the Evaluation of a Novel Hypoxic 3D Pancreatic Cancer Model as a Tool for Radiotherapy Treatment Screening. Cancers. 2021;13(23):6080. doi:10.3390/cancers13236080

Jennifer M. Rosenbluth, Ron C. J. Schackmann, G. Kenneth Gray, et al. Organoid cultures from normal and cancer-prone human breast tissues preserve complex epithelial lineages. Nature Communications. 2020;11(1):1711. doi:10.1038/s41467-020-15548-7

Else Driehuis, Kai Kretzschmar, Hans Clevers. Establishment of patient-derived cancer organoids for drug-screening applications. Nature Protocols. 2020;15(10):3380-3409. doi:10.1038/s41596-020-0379-4

Kanako Yuki, Ning Cheng, Michitaka Nakano, Calvin J. Kuo. Organoid Models of Tumor Immunology. Trends in Immunology. 2020;41(8):652-664. doi:10.1016/j.it.2020.06.010

David Tuveson, Hans Clevers. Cancer modeling meets human organoid technology. Science (New York, N.Y.). 2019;364(6444):952-955. doi:10.1126/science.aaw6985