Cancer

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Shivani Baisiwala, Elisa Fazzari, Matthew X. Li, et al. A human tumor-immune organoid model of glioblastoma. Cell Reports. 2026;45(1):116790. doi:10.1016/j.celrep.2025.116790
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Jerome Lacombe, Sean E. Dunn, Marie Layac, et al. A human 3D culture-organ-on-chip platform for investigating the tumor microenvironment response to ionizing radiation. iScience. 2026;29(1). doi:10.1016/j.isci.2025.114236
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Pooja Sawant, Ratnesh Jain, Prajakta Dandekar. Emerging therapies for lung adenocarcinoma: Mechanistic and efficacy insights from spheroid-based <i>in vitro</i> models. Journal of Drug Delivery Science and Technology. 2026;117:108030. doi:10.1016/j.jddst.2026.108030
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Hui-Hsuan Kuo, Bhavneet Bhinder, Hamza N. Gokozan, et al. Patient-derived organoids across cancers reveal conserved tumor heterogeneity and actionable therapeutic vulnerabilities. Science Advances. 2026;12(26):eadz3351. doi:10.1126/sciadv.adz3351
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Dina ElHarouni, Mushriq Al-Jazrawe, Seongmin Choi, et al. A compendium of next-generation patient-derived models for diverse cancers. Nature. 2026:1-14. doi:10.1038/s41586-026-10806-y
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Enrique Podaza, Jared Capuano, Hui-Hsuan Kuo, et al. Tumor immune microenvironment reconstitution in patient-derived organoids enables therapy modeling for NSCLC. Cell Reports Methods. 2026;6(6). doi:10.1016/j.crmeth.2026.101339
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Julius Thyen, Victor A. Sioson, Daniel Haak, et al. A pancreatic cancer organoid-macrophage co-culture using starPEG-heparin hydrogel deciphers tumor-immune cell interactions. npj Precision Oncology. 2026;10(1):343. doi:10.1038/s41698-026-01678-6
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Alan G. Chramiec, Ilaria Baldassarri, Ece Öztürk, et al. Organ-specific colonization and niche remodeling in a human tissue model of metastasis. Science Translational Medicine. 2026;18(863):eadv6871. doi:10.1126/scitranslmed.adv6871
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