%0 Journal Article %K Animals %K Disease Models, Animal %K Drug Evaluation, Preclinical %K External validity %K Human-relevant methods %K Preclinical animal models %K Reproducibility of Results %K Species Specificity %K Translation %B Journal of Translational Medicine %D 2018 %G eng %N 1 %P 304 %R 10.1186/s12967-018-1678-1 %T Is it possible to overcome issues of external validity in preclinical animal research? Why most animal models are bound to fail %U https://translational-medicine.biomedcentral.com/articles/10.1186/s12967-018-1678-1 %V 16 %8 2018-11-07 %! Is it possible to overcome issues of external validity in preclinical animal research?