%0 Journal Article %K Drug Approval %K Drug development %K Germ-Line Mutation %K Human Genetics %K Humans %K Molecular Targeted Therapy %K Rare Diseases %K Therapies, Investigational %K Time Factors %B Nature %D 2023 %G eng %N 7975 %P 737-745 %R 10.1038/s41586-023-06388-8 %T From target discovery to clinical drug development with human genetics %V 620 %8 2023-08