%0 Journal Article %K Autism Spectrum Disorder %K Autistic Disorder %K Brain %K CRISPR-Associated Protein 9 %K CRISPR-Cas Systems %K Cell Lineage %K Chromatin %K Developmental Disabilities %K Gene Editing %K Humans %K Loss of Function Mutation %K Mosaicism %K Neurons %K organoids %K RNA, Guide, CRISPR-Cas Systems %K Single-Cell Gene Expression Analysis %K Transcription, Genetic %B Nature %D 2023 %G eng %N 7978 %P 373-380 %R 10.1038/s41586-023-06473-y %T Single-cell brain organoid screening identifies developmental defects in autism %V 621 %8 2023-09