%0 Journal Article
%K FDA, U.S. Food and Drug Administration
%K LR, likelihood ratio
%K NLR, negative likelihood ratio
%K NPV, negative predictive value
%K PLR, positive likelihood ratio
%K PPV, positive predictive value
%K animal research
%K Drug development
%K toxicity
%K translational research
%B JACC. Basic to translational science
%D 2019
%G eng
%N 7
%P 845-854
%R 10.1016/j.jacbts.2019.10.008
%T Limitations of Animal Studies for Predicting Toxicity in Clinical Trials: Is it Time to Rethink Our Current Approach?
%U https://www.sciencedirect.com/science/article/pii/S2452302X1930316X?via%3Dihub
%V 4
%8 2019-11
%! Limitations of Animal Studies for Predicting Toxicity in Clinical Trials