TY - JOUR
KW - Registered Reports
KW - preregistration
KW - Publication Bias
KW - selective reporting
KW - severe testing
AU - Daniël Lakens
AU - Cristian Mesquida
AU - Sajedeh Rasti
AU - Massimiliano Ditroilo
AB - Practices that introduce systematic bias are common in most scientific disciplines, including toxicology. Selective reporting of results and publication bias are two of the most prevalent sources of bias and lead to unreliable scientific claims. Preregistration and Registered Reports are recent developments that aim to counteract systematic bias and allow other scientists to transparently evaluate how severely a claim has been tested. We review metascientific research confirming that preregistration and Registered Reports achieve their goals, and have additional benefits, such as improving the quality of studies. We then reflect on criticisms of preregistration. Beyond the valid concern that the mere presence of a preregistration may be mindlessly used as a proxy for high quality, we identify conflicting viewpoints, several misunderstandings, and a general lack of empirical support for the criticisms that have been raised. We conclude with general recommendations to increase the quality and practice of preregistration.
BT - Evidence-Based Toxicology
DA - 2024-12-31
DO - 10.1080/2833373X.2024.2376046
IS - 1
N2 - Practices that introduce systematic bias are common in most scientific disciplines, including toxicology. Selective reporting of results and publication bias are two of the most prevalent sources of bias and lead to unreliable scientific claims. Preregistration and Registered Reports are recent developments that aim to counteract systematic bias and allow other scientists to transparently evaluate how severely a claim has been tested. We review metascientific research confirming that preregistration and Registered Reports achieve their goals, and have additional benefits, such as improving the quality of studies. We then reflect on criticisms of preregistration. Beyond the valid concern that the mere presence of a preregistration may be mindlessly used as a proxy for high quality, we identify conflicting viewpoints, several misunderstandings, and a general lack of empirical support for the criticisms that have been raised. We conclude with general recommendations to increase the quality and practice of preregistration.
PY - 2024
EP - 2376046
T2 - Evidence-Based Toxicology
TI - The benefits of preregistration and Registered Reports
UR - https://doi.org/10.1080/2833373X.2024.2376046
VL - 2
Y2 - 2024-08-13
SN - null
ER -