TY - JOUR KW - animal models KW - Drug development KW - Preclinical research KW - clinical trials KW - predic3ve methods AU - Thomas Hartung AB -

Animals like mice and rats have long been used in medical research to help understand disease and test potential new treatments before human trials. However, while animal studies have contributed to important advances, too much reliance on animal models can also mislead drug development. This article explains for a general audience how animal research is used to develop new medicines, its benefits and limitations, and how more accurate and humane techniques—alternatives to animal testing—could improve this process.

BT - Frontiers in Drug Discovery DA - 2024-04-08 DO - 10.3389/fddsv.2024.1355044 LA - English N2 -

Animals like mice and rats have long been used in medical research to help understand disease and test potential new treatments before human trials. However, while animal studies have contributed to important advances, too much reliance on animal models can also mislead drug development. This article explains for a general audience how animal research is used to develop new medicines, its benefits and limitations, and how more accurate and humane techniques—alternatives to animal testing—could improve this process.

PY - 2024 T2 - Frontiers in Drug Discovery TI - The (misleading) role of animal models in drug development UR - https://www.frontiersin.org/journals/drug-discovery/articles/10.3389/fddsv.2024.1355044/full VL - 4 Y2 - 2024-08-13 SN - 2674-0338 ER -