TY - JOUR
AU - Eric Courchesne
AU - Vani Taluja
AU - Sanaz Nazari
AU - Caitlin M. Aamodt
AU - Karen Pierce
AU - Kuaikuai Duan
AU - Sunny Stophaeros
AU - Linda Lopez
AU - Cynthia Carter Barnes
AU - Jaden Troxel
AU - Kathleen Campbell
AU - Tianyun Wang
AU - Kendra Hoekzema
AU - Evan E. Eichler
AU - Joao V. Nani
AU - Wirla Pontes
AU - Sandra Sanchez Sanchez
AU - Michael V. Lombardo
AU - Janaina S. de Souza
AU - Mirian A. F. Hayashi
AU - Alysson R. Muotri
AB - Social affective and communication symptoms are central to autism spectrum disorder (ASD), yet their severity differs across toddlers: Some toddlers with ASD display improving abilities across early ages and develop good social and language skills, while others with “profound” autism have persistently low social, language and cognitive skills and require lifelong care. The biological origins of these opposite ASD social severity subtypes and developmental trajectories are not known.
BT - Molecular Autism
DA - 2024-05-25
DO - 10.1186/s13229-024-00602-8
IS - 1
N2 - Social affective and communication symptoms are central to autism spectrum disorder (ASD), yet their severity differs across toddlers: Some toddlers with ASD display improving abilities across early ages and develop good social and language skills, while others with “profound” autism have persistently low social, language and cognitive skills and require lifelong care. The biological origins of these opposite ASD social severity subtypes and developmental trajectories are not known.
PY - 2024
EP - 22
ST - Embryonic origin of two ASD subtypes of social symptom severity
T2 - Molecular Autism
TI - Embryonic origin of two ASD subtypes of social symptom severity: the larger the brain cortical organoid size, the more severe the social symptoms
UR - https://doi.org/10.1186/s13229-024-00602-8
VL - 15
Y2 - 2024-08-13
SN - 2040-2392
ER -