TY - JOUR KW - Biomedical Research KW - Public Health KW - Societal impact KW - Translatability KW - Funding KW - patient-centric research KW - policy KW - research innovative methodologies AU - Francesca Pistollato AU - Gregor Burkhart AU - Pierre Deceuninck AU - Camilla Bernasconi AU - Sergio Di Virgilio AU - Luca Emili AU - Anne-Charlotte Fauvel AU - Luisa Ferreira Bastos AU - Annalisa Gastaldello AU - Chiara Gerardi AU - Jens K. Habermann AU - Ioan Hanes AU - Christina Kyriakopoulou AU - Uma Lanka AU - Paolo Lauriola AU - Hugh Laverty AU - Benoît G. C. Maisonneuve AU - Milena Mennecozzi AU - Francesco Pappalardo AU - Roberta Pastorino AU - Vilma Radvilaite AU - Erwin L. Roggen AU - Helder Constantino AB -

In the past decade, significant European calls for research proposals have supported translational collaborative research on non-communicable and infectious diseases within the biomedical life sciences by bringing together interdisciplinary and multinational consortia. This research has advanced our understanding of disease pathophysiology, marking considerable scientific progress. Yet, it is crucial to retrospectively evaluate these efforts’ societal impact. Research proposals should be thoughtfully designed to ensure that the research findings can be effectively translated into actionable policies. In addition, the choice of scientific methods plays a pivotal role in shaping the societal impact of research discoveries. Understanding the factors responsible for current unmet public health issues and medical needs is crucial for crafting innovative strategies for research policy interventions. A multistakeholder survey and a roundtable helped identify potential needs for consideration in the EU research and policy agenda. Based on survey findings, mental health disorders, metabolic syndrome, cancer, antimicrobial resistance, environmental pollution, and cardiovascular diseases were considered the public health challenges deserving prioritisation. In addition, early diagnosis, primary prevention, the impact of environmental pollution on disease onset and personalised medicine approaches were the most selected unmet medical needs. Survey findings enabled the formulation of some research-policies interventions (RPIs), which were further discussed during a multistakeholder online roundtable. The discussion underscored recent EU-level activities aligned with the survey-derived RPIs and facilitated an exchange of perspectives on public health and biomedical research topics ripe for interdisciplinary collaboration and warranting attention within the EU’s research and policy agenda. Actionable recommendations aimed at facilitating the translation of knowledge into transformative, science-based policies are also provided.

BT - Frontiers in Public Health DA - 2024-07-22 DO - 10.3389/fpubh.2024.1417684 LA - English N2 -

In the past decade, significant European calls for research proposals have supported translational collaborative research on non-communicable and infectious diseases within the biomedical life sciences by bringing together interdisciplinary and multinational consortia. This research has advanced our understanding of disease pathophysiology, marking considerable scientific progress. Yet, it is crucial to retrospectively evaluate these efforts’ societal impact. Research proposals should be thoughtfully designed to ensure that the research findings can be effectively translated into actionable policies. In addition, the choice of scientific methods plays a pivotal role in shaping the societal impact of research discoveries. Understanding the factors responsible for current unmet public health issues and medical needs is crucial for crafting innovative strategies for research policy interventions. A multistakeholder survey and a roundtable helped identify potential needs for consideration in the EU research and policy agenda. Based on survey findings, mental health disorders, metabolic syndrome, cancer, antimicrobial resistance, environmental pollution, and cardiovascular diseases were considered the public health challenges deserving prioritisation. In addition, early diagnosis, primary prevention, the impact of environmental pollution on disease onset and personalised medicine approaches were the most selected unmet medical needs. Survey findings enabled the formulation of some research-policies interventions (RPIs), which were further discussed during a multistakeholder online roundtable. The discussion underscored recent EU-level activities aligned with the survey-derived RPIs and facilitated an exchange of perspectives on public health and biomedical research topics ripe for interdisciplinary collaboration and warranting attention within the EU’s research and policy agenda. Actionable recommendations aimed at facilitating the translation of knowledge into transformative, science-based policies are also provided.

PY - 2024 EP - 1417684 ST - What public health challenges and unmet medical needs would benefit from interdisciplinary collaboration in the EU? T2 - Frontiers in Public Health TI - What public health challenges and unmet medical needs would benefit from interdisciplinary collaboration in the EU? A survey and multi-stakeholder debate UR - https://www.frontiersin.org/journals/public-health/articles/10.3389/fpubh.2024.1417684/full VL - 12 Y2 - 2024-07-29 SN - 2296-2565 ER -