TY - JOUR
AU - Robert Jordan
AU - Stephanie L Ford-Scheimer
AU - Rodolfo M Alarcon
AU - Anthony Atala
AU - Jeffrey T Borenstein
AU - Kyle R Brimacombe
AU - Sara Cherry
AU - Hans Clevers
AU - Mindy I Davis
AU - Simon G P Funnell
AU - Lee Gehrke
AU - Linda G Griffith
AU - Abigail C Grossman
AU - Thomas Hartung
AU - Donald E Ingber
AU - Nicole C Kleinstreuer
AU - Calvin J Kuo
AU - Emily M Lee
AU - Christine L Mummery
AU - Thames E Pickett
AU - Sasirekha Ramani
AU - Edwin A Rosado-Olivieri
AU - Evi B Struble
AU - Zhengpeng Wan
AU - Mark S Williams
AU - Matthew D Hall
AU - Marc Ferrer
AU - Sarine Markossian
AB - The National Center for Advancing Translational Sciences (NCATS) Assay Guidance Manual (AGM) Workshop on 3D Tissue Models for Antiviral Drug Development, held virtually on 7–8 June 2022, provided comprehensive coverage of critical concepts intended to help scientists establish robust, reproducible, and scalable 3D tissue models to study viruses with pandemic potential. This workshop was organized by NCATS, the National Institute of Allergy and Infectious Diseases, and the Bill and Melinda Gates Foundation. During the workshop, scientific experts from academia, industry, and government provided an overview of 3D tissue models’ utility and limitations, use of existing 3D tissue models for antiviral drug development, practical advice, best practices, and case studies about the application of available 3D tissue models to infectious disease modeling. This report includes a summary of each workshop session as well as a discussion of perspectives and challenges related to the use of 3D tissues in antiviral drug discovery.
BT - The Journal of Infectious Diseases
DA - 2023-09-05
DO - 10.1093/infdis/jiad334
N2 - The National Center for Advancing Translational Sciences (NCATS) Assay Guidance Manual (AGM) Workshop on 3D Tissue Models for Antiviral Drug Development, held virtually on 7–8 June 2022, provided comprehensive coverage of critical concepts intended to help scientists establish robust, reproducible, and scalable 3D tissue models to study viruses with pandemic potential. This workshop was organized by NCATS, the National Institute of Allergy and Infectious Diseases, and the Bill and Melinda Gates Foundation. During the workshop, scientific experts from academia, industry, and government provided an overview of 3D tissue models’ utility and limitations, use of existing 3D tissue models for antiviral drug development, practical advice, best practices, and case studies about the application of available 3D tissue models to infectious disease modeling. This report includes a summary of each workshop session as well as a discussion of perspectives and challenges related to the use of 3D tissues in antiviral drug discovery.
PY - 2023
EP - jiad334
T2 - The Journal of Infectious Diseases
TI - Report of the Assay Guidance Workshop on 3-Dimensional Tissue Models for Antiviral Drug Development
UR - https://doi.org/10.1093/infdis/jiad334
Y2 - 2023-10-02
SN - 0022-1899
ER -