TY - JOUR
KW - Humanities and Social Sciences
KW - Science
KW - multidisciplinary
AU - Sheila MacNeil
AB - Tissue-engineered skin is now a reality. For patients with extensive full-thickness burns, laboratory expansion of skin cells to achieve barrier function can make the difference between life and death, and it was this acute need that drove the initiation of tissue engineering in the 1980s. A much larger group of patients have ulcers resistant to conventional healing, and treatments using cultured skin cells have been devised to restart the wound-healing process. In the laboratory, the use of tissue-engineered skin provides insight into the behaviour of skin cells in healthy skin and in diseases such as vitiligo, melanoma, psoriasis and blistering disorders.
BT - Nature
DA - 2007-02
DO - 10.1038/nature05664
IS - 7130
LA - en
N2 - Tissue-engineered skin is now a reality. For patients with extensive full-thickness burns, laboratory expansion of skin cells to achieve barrier function can make the difference between life and death, and it was this acute need that drove the initiation of tissue engineering in the 1980s. A much larger group of patients have ulcers resistant to conventional healing, and treatments using cultured skin cells have been devised to restart the wound-healing process. In the laboratory, the use of tissue-engineered skin provides insight into the behaviour of skin cells in healthy skin and in diseases such as vitiligo, melanoma, psoriasis and blistering disorders.
PY - 2007
SP - 874
EP - 880
T2 - Nature
TI - Progress and opportunities for tissue-engineered skin
UR - https://www.nature.com/articles/nature05664
VL - 445
Y2 - 2023-09-15
SN - 1476-4687
ER -