TY - ECHAP AU - John J. Pippin AU - Sarah E. Cavanaugh AU - Francesca Pistollato AU - Kathrin Herrmann AU - Kimberley Jayne AB - Perhaps the most impactful and foreboding development in chronic diseases in recent decades has been the increasing prevalence and awareness of dementia. The various dementias, especially Alzheimer disease (AD), have derailed and ended the lives of tens of millions in America and worldwide. It is a truism that AD patients die twice. First the mind dies, and only later does the body. AD uniquely and unremittingly affects not only patients, but their families, caregivers, and communities. In recent years, AD may have displaced cancer as the most feared disease among Americans. As with other diseases that have no meaningful methods BT - Animal Experimentation: Working Towards a Paradigm Change DA - 2019 N2 - Perhaps the most impactful and foreboding development in chronic diseases in recent decades has been the increasing prevalence and awareness of dementia. The various dementias, especially Alzheimer disease (AD), have derailed and ended the lives of tens of millions in America and worldwide. It is a truism that AD patients die twice. First the mind dies, and only later does the body. AD uniquely and unremittingly affects not only patients, but their families, caregivers, and communities. In recent years, AD may have displaced cancer as the most feared disease among Americans. As with other diseases that have no meaningful methods PB - Brill PY - 2019 SP - 480 EP - 516 ST - Animal Research for Alzheimer Disease T2 - Animal Experimentation: Working Towards a Paradigm Change TI - Animal Research for Alzheimer Disease: Failures of Science and Ethics UR - https://www.jstor.org/stable/10.1163/j.ctvjhzq0f.27 Y2 - 2022-12-01 ER -