TY - JOUR
KW - Cancer
KW - Drug screening
KW - organoid
KW - Organoid Biobank
KW - Precision Medicine
AU - Zhen Fang
AU - Peijuan Li
AU - Fengying Du
AU - Liang Shang
AU - Leping Li
AB - Organoids are established through in vitro 3D culture, and they can mimic the structure and physiological functions of organs or tissues in vivo. Organoids have attracted much attention in recent years. They can provide a reliable technology platform for cancer research and treatment and are a valuable preclinical model for academic research and personalized medicine. A number of studies have confirmed that organoids have great application prospects in new drug development, drug screening, tumour mechanism research, and precision medicine. In this review, we mainly focus on recent advances in the application of organoids in cancer research. We also discussed the opportunities and challenges facing organoids, hoping to indicate directions for the development of organoids in the future.
BT - Experimental Hematology & Oncology
DA - 2023-08-03
DO - 10.1186/s40164-023-00433-y
IS - 1
LA - en
N2 - Organoids are established through in vitro 3D culture, and they can mimic the structure and physiological functions of organs or tissues in vivo. Organoids have attracted much attention in recent years. They can provide a reliable technology platform for cancer research and treatment and are a valuable preclinical model for academic research and personalized medicine. A number of studies have confirmed that organoids have great application prospects in new drug development, drug screening, tumour mechanism research, and precision medicine. In this review, we mainly focus on recent advances in the application of organoids in cancer research. We also discussed the opportunities and challenges facing organoids, hoping to indicate directions for the development of organoids in the future.
PY - 2023
EP - 69
T2 - Experimental Hematology & Oncology
TI - The role of organoids in cancer research
UR - https://doi.org/10.1186/s40164-023-00433-y
VL - 12
Y2 - 2023-09-11
SN - 2162-3619
ER -