TY - JOUR
KW - Kidney failure
KW - organ-on-a-chip
KW - Severe acute respiratory syndrome
KW - bioMEMS
AU - Holly Ryan
AU - Chelsey S. Simmons
AB - The kidneys are susceptible to adverse effects from many diseases, including several that are not tissue-specific. Acute kidney injury is a common complication of systemic diseases such as diabetes, lupus, and certain infections including the novel coronavirus (SARS-CoV-2). Microfluidic devices are an attractive option for disease modeling, offering the opportunity to utilize human cells, control experimental and environmental conditions, and combine with other on-chip devices. For researchers with expertise in microfluidics, this brief perspective highlights potential applications of such devices to studying SARS-CoV-2-induced kidney injury.
BT - Cellular and Molecular Bioengineering
DA - 2020-08-01
DO - 10.1007/s12195-020-00649-6
IS - 4
LA - en
N2 - The kidneys are susceptible to adverse effects from many diseases, including several that are not tissue-specific. Acute kidney injury is a common complication of systemic diseases such as diabetes, lupus, and certain infections including the novel coronavirus (SARS-CoV-2). Microfluidic devices are an attractive option for disease modeling, offering the opportunity to utilize human cells, control experimental and environmental conditions, and combine with other on-chip devices. For researchers with expertise in microfluidics, this brief perspective highlights potential applications of such devices to studying SARS-CoV-2-induced kidney injury.
PY - 2020
SP - 305
EP - 311
T2 - Cellular and Molecular Bioengineering
TI - Potential Applications of Microfluidics to Acute Kidney Injury Associated with Viral Infection
UR - https://doi.org/10.1007/s12195-020-00649-6
VL - 13
Y2 - 2023-08-09
SN - 1865-5033
ER -