TY - JOUR
KW - Diseases
KW - Materials science
KW - Nanoscience and technology
KW - Virology
AU - Zhongmin Tang
AU - Na Kong
AU - Xingcai Zhang
AU - Yuan Liu
AU - Ping Hu
AU - Shan Mou
AU - Peter Liljeström
AU - Jianlin Shi
AU - Weihong Tan
AU - Jong Seung Kim
AU - Yihai Cao
AU - Robert Langer
AU - Kam W. Leong
AU - Omid C. Farokhzad
AU - Wei Tao
AB - The ongoing SARS-CoV-2 pandemic highlights the importance of materials science in providing tools and technologies for antiviral research and treatment development. In this Review, we discuss previous efforts in materials science in developing imaging systems and microfluidic devices for the in-depth and real-time investigation of viral structures and transmission, as well as material platforms for the detection of viruses and the delivery of antiviral drugs and vaccines. We highlight the contribution of materials science to the manufacturing of personal protective equipment and to the design of simple, accurate and low-cost virus-detection devices. We then investigate future possibilities of materials science in antiviral research and treatment development, examining the role of materials in antiviral-drug design, including the importance of synthetic material platforms for organoids and organs-on-a-chip, in drug delivery and vaccination, and for the production of medical equipment. Materials-science-based technologies not only contribute to the ongoing SARS-CoV-2 research efforts but can also provide platforms and tools for the understanding, protection, detection and treatment of future viral diseases.
BT - Nature Reviews Materials
DA - 2020-11
DO - 10.1038/s41578-020-00247-y
IS - 11
LA - en
N2 - The ongoing SARS-CoV-2 pandemic highlights the importance of materials science in providing tools and technologies for antiviral research and treatment development. In this Review, we discuss previous efforts in materials science in developing imaging systems and microfluidic devices for the in-depth and real-time investigation of viral structures and transmission, as well as material platforms for the detection of viruses and the delivery of antiviral drugs and vaccines. We highlight the contribution of materials science to the manufacturing of personal protective equipment and to the design of simple, accurate and low-cost virus-detection devices. We then investigate future possibilities of materials science in antiviral research and treatment development, examining the role of materials in antiviral-drug design, including the importance of synthetic material platforms for organoids and organs-on-a-chip, in drug delivery and vaccination, and for the production of medical equipment. Materials-science-based technologies not only contribute to the ongoing SARS-CoV-2 research efforts but can also provide platforms and tools for the understanding, protection, detection and treatment of future viral diseases.
PY - 2020
SP - 847
EP - 860
T2 - Nature Reviews Materials
TI - A materials-science perspective on tackling COVID-19
UR - https://www.nature.com/articles/s41578-020-00247-y
VL - 5
Y2 - 2023-08-09
SN - 2058-8437
ER -